S
Sohn Kim
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 8
Citations - 987
Sohn Kim is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Colonisation resistance & Transplantation. The author has an hindex of 5, co-authored 8 publications receiving 621 citations. Previous affiliations of Sohn Kim include Cornell University.
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Journal ArticleDOI
The intestinal microbiota: Antibiotics, colonization resistance, and enteric pathogens.
TL;DR: The members of the microbiota, as well as the mechanisms, that govern colonization resistance against specific pathogens are discussed, aswell as the unique epidemiology of immunocompromised patients that renders them a particularly high‐risk population to intestinal nosocomial infections.
Journal ArticleDOI
Cooperating Commensals Restore Colonization Resistance to Vancomycin-Resistant Enterococcus faecium
Silvia Caballero,Sohn Kim,Rebecca A. Carter,Ingrid Leiner,Bože Sušac,Liza Miller,Grace Kim,Lilan Ling,Eric G. Pamer,Eric G. Pamer +9 more
TL;DR: These findings suggest that therapeutic or prophylactic administration of defined bacterial consortia to individuals with compromised microbiota composition may reduce inter-patient transmission and intra-patient dissemination of highly antibiotic-resistant pathogens.
Journal ArticleDOI
Commensal microbes provide first line defense against Listeria monocytogenes infection.
Simone Becattini,Eric R. Littmann,Rebecca A. Carter,Sohn Kim,Sejal Morjaria,Lilan Ling,Yangtsho Gyaltshen,Emily Fontana,Ying Taur,Ingrid Leiner,Eric G. Pamer +10 more
TL;DR: It is shown that a diverse microbiota markedly reduces Listeria monocytogenes colonization of the gut lumen and prevents systemic dissemination, and identifies intestinal commensal species that, by enhancing resistance against this pathogen, represent potential probiotics.
Journal ArticleDOI
Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus
Sohn Kim,Sohn Kim,Simone Becattini,Thomas U. Moody,Pavel V. Shliaha,Eric R. Littmann,Ruth Seok,Mergim Gjonbalaj,Vincent Eaton,Emily Fontana,Luigi A Amoretti,Roberta J. Wright,Silvia Caballero,Silvia Caballero,Zhong Min X. Wang,Hea Jin Jung,Sejal Morjaria,Ingrid Leiner,Weige Qin,Ruben J. Ramos,Justin R. Cross,Seiko Narushima,Kenya Honda,Jonathan U. Peled,Jonathan U. Peled,Ronald C. Hendrickson,Ying Taur,Marcel R.M. van den Brink,Marcel R.M. van den Brink,Eric G. Pamer +29 more
TL;DR: It is shown that BPSCSK reduces growth of VRE by secreting a lantibiotic that is similar to the nisin-A produced by Lactococcus lactis, which represents potential probiotic agents to re-establish resistance to VRE.
Journal ArticleDOI
Rapid transcriptional and metabolic adaptation of intestinal microbes to host immune activation
Simone Becattini,Simone Becattini,Matthew T. Sorbara,Sohn Kim,Eric L. Littmann,Qiwen Dong,Gavin Walsh,Roberta J. Wright,Luigi A Amoretti,Emily Fontana,Tobias M. Hohl,Eric G. Pamer +11 more
TL;DR: In this article, the authors colonized mice with four anaerobic symbionts and showed that acute immune responses result in dramatic transcriptional reprogramming of these commensals with minimal changes in their relative abundance.