Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar,Mohali, Punjab-160 062, India, Institute of Biochemistry, Faculty of Medicine, Polytechnic University, Via Ranieri 67, IT-60100 Ancona, Italy,Green Biotechnology Research Group, The Special Division for Human Life Technology, National Institute of Advanced Industrial Science andTechnology, 1-8-31 Midorigaoka, Ikeda, Osaka-563-8577, Japan, and Department of Medicinal Chemistry & Natural Products,The Hebrew University of Jerusalem, School of Pharmacy-Faculty of Medicine, Jerusalem 91120, IsraelReceived March 2, 2004

Chitosan chemistry and pharmaceutical perspectives.

The Stability of Cyclodextrin Complexes in Solution.

NMR Studies of Cyclodextrins and Cyclodextrin Complexes

Review: a history of cyclodextrins.

The supramolecular crosslinking of polymer chains in water by specific, directional and dynamic non-covalent interactions has led to the development of novel supramolecular polymeric hydrogels. These aqueous polymeric networks constitute an interesting class of soft materials exhibiting attractive properties such as stimuli-responsiveness and self-healing arising from their dynamic behaviour and that are crucial for a wide variety of emerging applications. We present here a critical review summarising the formation of dynamic polymeric networks through specific non-covalent interactions, with a particular emphasis on those systems based on host–guest complex formation, as well as the characterisation of their physical characteristics. Aqueous supramolecular chemistry has unlocked a versatile toolbox for the design and fine-tuning of the material properties of these hydrogels (264 references).

Supramolecular polymeric hydrogels

Cyclodextrins and their applications in analytical chemistry

Fused-silica capillaries of 50-μm internal diameter were packed with an α 1 -acid glycoprotein chiral stationary phase. The properties of electroosmosis in these packed capillaries were studied by investigating the influence of field strength, pH, and solvent composition on the velocity of electroosmotic flow. Direct enantiomeric separation by capillary electrochromatography was investigated with the use of these packed capillaries

Direct chiral separations by capillary electrophoresis using capillaries packed with an .alpha.1-acid glycoprotein chiral stationary phase

Packed-capillary electrochromatographic separation of the enantiomers of neutral and anionic compounds using β-cyclodextrin as a chiral selector: Effect of operating parameters and comparison with free-solution capillary electrophoresis

Protein chiral selectors in free-solution capillary electrophoresis and packed-capillary electrochromatography

The chiral recognition mechanism of β-cyclodextrin was studied by UV-visible, circular dichroism, and proton nuclear magnetic resonance spectroscopic methods. The D and L enantiomers of DNP-valine, DNP-leucine, and DNP-methionine were used as model solutes. The results indicate that the dinitrophenyl group, which forms stable inclusion complexes with the β-cyclodextrin cavity and places the other functional groups around the chiral center in association with the hydroxyl groups at the edge of the cavity, plays a very important role in the chiral recognition

Circular dichroism, ultraviolet, and proton nuclear magnetic resonance spectroscopic studies of the chiral recognition mechanism of .beta.-cyclodextrin

Song Li

Papers

Cyclodextrins and their applications in analytical chemistry

Direct chiral separations by capillary electrophoresis using capillaries packed with an .alpha.1-acid glycoprotein chiral stationary phase

Packed-capillary electrochromatographic separation of the enantiomers of neutral and anionic compounds using β-cyclodextrin as a chiral selector: Effect of operating parameters and comparison with free-solution capillary electrophoresis

Protein chiral selectors in free-solution capillary electrophoresis and packed-capillary electrochromatography

Circular dichroism, ultraviolet, and proton nuclear magnetic resonance spectroscopic studies of the chiral recognition mechanism of .beta.-cyclodextrin