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Sonny Khin

Researcher at Pennsylvania State University

Publications -  11
Citations -  2138

Sonny Khin is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Cancer & Retina. The author has an hindex of 7, co-authored 11 publications receiving 2020 citations. Previous affiliations of Sonny Khin include Penn State Milton S. Hershey Medical Center & University of Texas Health Science Center at Houston.

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Journal ArticleDOI

Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin.

Alistair J. Barber, +5 more
- 15 Aug 1998 - 
TL;DR: This is the first quantitative report of an increase in neural cell apoptosis in the retina during diabetes, and indicates that neurodegeneration is an important component of diabetic retinopathy.
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Vascular permeability in experimental diabetes is associated with reduced endothelial occludin content: vascular endothelial growth factor decreases occludin in retinal endothelial cells. Penn State Retina Research Group.

David A. Antonetti, +5 more
- 01 Dec 1998 - 
TL;DR: These data show that diabetes selectively reduces retinal occludin protein expression and increases BRB permeability, and suggest that the elevated VEGF in the vitreous of patients with diabetic retinopathy increases vascular permeability by downregulating occlUDin content.
Journal Article

Astrocytes Increase Barrier Properties and ZO-1 Expression in Retinal Vascular Endothelial Cells

Thomas W. Gardner, +7 more
- 01 Oct 1997 - 
TL;DR: The results suggest that astrocytes enhance blood-retinal barrier properties, at least in part by increasing tight junction protein expression, and suggest that glial malfunction plays an important role in the pathogenesis of vasogenic retinal edema.
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Histamine reduces ZO-1 tight-junction protein expression in cultured retinal microvascular endothelial cells.

Thomas W. Gardner, +5 more
- 15 Dec 1996 - 
TL;DR: Histamine reduces ZO-1 expression within the time associated with increased paracellular permeability, suggesting that tight-junction-protein alterations may be a novel explanation for the mechanism by which vasoactive agents increase microvascular permeability.
Journal Article

Hormonal Regulation of Insulin-like Growth Factor II and Insulin-like Growth Factor Binding Protein Expression by Breast Cancer Cells in Vivo: Evidence for Stromal Epithelial Interactions

Andrea Manni, +8 more
- 01 Jun 1994 - 
TL;DR: It is concluded that hormonal regulation of IGFBP expression is heterogeneous, thus suggesting divergent biological functions for these peptides in the control of breast cancer cell proliferation by IGFs.