S
Soyeon Kim
Researcher at University of Texas Southwestern Medical Center
Publications - 5
Citations - 2059
Soyeon Kim is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Actin & Transmembrane protein. The author has an hindex of 4, co-authored 5 publications receiving 1514 citations. Previous affiliations of Soyeon Kim include Howard Hughes Medical Institute & Marine Biological Laboratory.
Papers
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Journal ArticleDOI
Phase transitions in the assembly of multivalent signalling proteins
Pilong Li,Sudeep Banjade,Hui-Chun Cheng,Soyeon Kim,Baoyu Chen,Liang Guo,Marc C. Llaguno,Javoris Hollingsworth,David S. King,Salman F. Banani,Paul S. Russo,Qiu-Xing Jiang,B. Tracy Nixon,Michael K. Rosen +13 more
TL;DR: Interactions between diverse synthetic, multivalent macromolecules (including multi-domain proteins and RNA) produce sharp liquid–liquid-demixing phase separations, generating micrometre-sized liquid droplets in aqueous solution.
Journal ArticleDOI
Hierarchical regulation of WASP/WAVE proteins.
Shae B. Padrick,Hui-Chun Cheng,Ayman M. Ismail,Sanjay C. Panchal,Lynda K. Doolittle,Soyeon Kim,Brian M. Skehan,Junko Umetani,Chad A. Brautigam,John M. Leong,Michael K. Rosen +10 more
TL;DR: Dimmerization increases the affinity of active WASP species for Arp2/3 complex by up to 180-fold, greatly enhancing actin assembly by this system, and explains a large and apparently disparate set of observations under a common mechanistic framework.
Journal ArticleDOI
Phosphorylation of Nephrin induces phase separated domains that move through actomyosin contraction
Soyeon Kim,Joseph Mathew Kalappurakkal,Satyajit Mayor,Satyajit Mayor,Michael K. Rosen,Michael K. Rosen +5 more
TL;DR: These studies illustrate how multivalent interactions between proteins at the plasma membrane can produce micron-scale organization of signaling molecules, and how the resulting clusters can both respond to and control the actin cytoskeleton.
Journal ArticleDOI
Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives
Janjira Rujirawanich,Soyeon Kim,Ai-Jun Ma,John R. Butler,Yizhong Wang,Chao Wang,Michael K. Rosen,Bruce A. Posner,Deepak Nijhawan,Joseph M. Ready +9 more
TL;DR: Celluar studies reveal that kibdelone C and its simplified derivatives disrupt the actin cytoseketon without directly binding actin or affecting its polymerization in vitro.
Posted ContentDOI
Phosphorylation of Nephrin induces phase separated domains that move through actomyosin contraction
Soyeon Kim,Soyeon Kim,Joseph Mathew Kalappurakkal,Joseph Mathew Kalappurakkal,Satyajit Mayor,Satyajit Mayor,Michael K. Rosen,Michael K. Rosen +7 more
TL;DR: These studies illustrate how multivalent interactions between proteins at the plasma membrane can produce micron-scale organization of signaling molecules, and how the resulting clusters can both respond to and control the actin cytoskeleton.