Sridhar Krishnaswamy

Bio: Sridhar Krishnaswamy is an academic researcher from Northwestern University. The author has contributed to research in topics: Ultrasonic sensor & Interferometry. The author has an hindex of 31, co-authored 274 publications receiving 3482 citations. Previous affiliations of Sridhar Krishnaswamy include International Institute of Minnesota & California Institute of Technology.

A coherent gradient sensor for crack tip deformation measurements: analysis and experimental results

Abstract: A first order diffraction analysis of an optical interferometer, Coherent Gradient Sensor (CGS), for measuring surface gradients is presented. Its applicability in the field of fracture mechanics is demonstrated by quantitatively measuring the gradients of out-of-plane displacements around a crack tip in a three point bent fracture specimen under static loading. This method has potential for the study of deformation fields near a quasi-statically or dynamically growing crack.

Response of a fiber Bragg grating ultrasonic sensor

Abstract: A fiber Bragg grating (FBG) sensor for detection of ultrasonic waves in liquids and solid structures is investigated. The sensor contains a fiber probe with a FBG, a tunable narrowband laser source, and a photodetector. When ultrasonic waves impinge on the fiber probe, the pitch of the grating is modulated through the elasto-optic effect. The corresponding changes in reflectivity of the grating are detected by a photodetector. The sensitivity of the sensor and its frequency and directional response in the 0.5 to 3.0 MHz range are measured. Some anomalous features of the FBG ultrasound sensor response are noted. It is shown that these features result from a combination of the sensor's response to the direct ultrasonic waves propagating through the medium and the signal generated by axially guided ultrasonic waves propagating through the fiber probe.

Optical mapping of crack tip deformations using the methods of transmission and reflection coherent gradient sensing - A study of crack tip K-dominance

Abstract: A new full field optical technique-‘Coherent Gradient Sensing’ (CGS)-is developed and used to study crack tip deformations in transparent as well as opaque solids. A first order diffraction analysis is provided for the technique and its feasibility is demonstrated both in transmission and reflection modes. Preliminary results from the dynamic crack growth experiment clearly demonstrate the capability of CGS to be an effective experimental alternative to other optical methods used in dynamic fracture studies. Notably, it is a full field technique which works with optically isotropic materials.

Fiber humidity sensors with high sensitivity and selectivity based on interior nanofilm-coated photonic crystal fiber long-period gratings

Abstract: A photonic crystal fiber (PCF) long-period grating (LPG) humidity sensor has been developed with high sensitivity and selectivity for nondestructive detection of moisture ingression into structures that can potentially lead to corrosion. We have proposed two types of nanofilms to be coated on the surface of air channels in the grating region by electrostatic self-assembly deposition processing. The primary nanofilm does not affect LPG properties such as resonance wavelength or transmission intensity which can impact sensing characteristics; however it increases the sensitivity by changing the refractive index of the surrounding material. The secondary nanofilm is used for selectively adsorbing analyte molecules of interest. The experimental results reveal that, compared to the conventional fiber LPGs and exterior nanofilm-coated PCF-LPG, the interior nanofilm-coated PCF-LPG humidity sensors have both the most sensitive resonance intensity change of 0.00022%/10 −3 dBm from relative humidity (RH) of 38% to 39% and average wavelength shift of 0.0007%/pm for a relative humidity variation from 22% to 29%. The proposed sensor shows excellent thermal stability as well.

Interaction of a scanning laser-generated ultrasonic line source with a surface-breaking flaw

Abstract: The scanning laser source (SLS) technique has been proposed recently as an effective way to investigate small surface-breaking cracks. By monitoring the amplitude and frequency changes of the ultrasound generated as the SLS scans over a defect, the SLS technique has provided enhanced signal-to-noise performance compared to the traditional pitch-catch or pulse-echo ultrasonic methods. In previous work, either a point source or a short line source was used for generation of ultrasound. The resulting Rayleigh wave was typically bipolar in nature. In this paper, a scanning laser line source (SLLS) technique using a true thermoelastic line source (which leads to generation of monopolar surface waves) is demonstrated experimentally and through numerical simulation. Experiments are performed using a line-focused Nd:YAG laser and interferometric detection. For the numerical simulation, a hybrid model combining a mass-spring lattice method (MSLM) and a finite difference method (FDM) is used. As the SLLS is scanned over a surface-breaking flaw, it is shown both experimentally and numerically that the monopolar Rayleigh wave becomes bipolar, dramatically indicating the presence of the flaw.

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

Phd by thesis

Abstract: Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These

Fourier-transform method of fringe-pattern analysis for computer-based topography and interferometry

Abstract: A fast-Fourier-transform method of topography and interferometry is proposed. By computer processing of a noncontour type of fringe pattern, automatic discrimination is achieved between elevation and depression of the object or wave-front form, which has not been possible by the fringe-contour-generation techniques. The method has advantages over moire topography and conventional fringe-contour interferometry in both accuracy and sensitivity. Unlike fringe-scanning techniques, the method is easy to apply because it uses no moving components.

Principles Of Optics Electromagnetic Theory Of Propagation Interference And Diffraction Of Light

Abstract: Thank you for reading principles of optics electromagnetic theory of propagation interference and diffraction of light. As you may know, people have search hundreds times for their favorite novels like this principles of optics electromagnetic theory of propagation interference and diffraction of light, but end up in harmful downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they are facing with some infectious bugs inside their computer.

Overview of three-dimensional shape measurement using optical methods

Abstract: We first provide an overview of 3-D shape measurement us- ing various optical methods. Then we focus on structured light tech- niques where various optical configurations, image acquisition tech- niques, data postprocessing and analysis methods and advantages and limitations are presented. Several industrial application examples are presented. Important areas requiring further R&D are discussed. Finally, a comprehensive bibliography on 3-D shape measurement is included, although it is not intended to be exhaustive. © 2000 Society of Photo-Optical Instrumentation Engineers. (S0091-3286(00)00101-X)