S
Srinivasa N. Raja
Researcher at Johns Hopkins University
Publications - 290
Citations - 24272
Srinivasa N. Raja is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Neuropathic pain & Hyperalgesia. The author has an hindex of 71, co-authored 287 publications receiving 20463 citations. Previous affiliations of Srinivasa N. Raja include Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.
Nanna B. Finnerup,Nadine Attal,Simon Haroutounian,Ewan D McNicol,Ralf Baron,Robert H. Dworkin,Ian Gilron,Maija Haanpää,Per Hansson,Per Hansson,Troels S. Jensen,Troels S. Jensen,Peter R. Kamerman,Karen Lund,Andrew Moore,Srinivasa N. Raja,Andrew S.C. Rice,Andrew S.C. Rice,Michael C. Rowbotham,Emily S. Sena,Emily S. Sena,Philip J. Siddall,Philip J. Siddall,Blair H. Smith,Mark S. Wallace +24 more
TL;DR: The results support a revision of the NeuPSIG recommendations for the pharmacotherapy of neuropathic pain and allow a strong recommendation for use and proposal as first-line treatment in neuropathicPain for tricyclic antidepressants, serotonin-noradrenaline reuptake inhibitors, pregabalin, and gabapentin.
Journal ArticleDOI
The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises.
Srinivasa N. Raja,Daniel B. Carr,Milton Cohen,Nanna B. Finnerup,Nanna B. Finnerup,Herta Flor,Stephen J. Gibson,Francis J. Keefe,Jeffrey S. Mogil,Matthias Ringkamp,Kathleen A. Sluka,Xue-Jun Song,Bonnie Stevens,Mark D. Sullivan,Perri R. Tutelman,Takahiro Ushida,Kyle Vader +16 more
TL;DR: This review provides a synopsis of the critical concepts, the analysis of comments from the IASP membership and public, and the committee's final recommendations for revisions to the definition and notes, which were discussed over a 2-year period.
Journal ArticleDOI
Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update
Robert H. Dworkin,Alec B. O'Connor,Joseph Audette,Ralf Baron,Geoffrey K. Gourlay,Maija Haanpää,Joel L. Kent,Elliot J. Krane,Elliot J. Krane,Alyssa Lebel,Robert M. Levy,Sean Mackey,John M. Mayer,Christine Miaskowski,Srinivasa N. Raja,Andrew S.C. Rice,Kenneth E. Schmader,Brett R. Stacey,Steven P. Stanos,Rolf-Detlef Treede,Dennis C. Turk,Gary A. Walco,Christopher D. Wells +22 more
TL;DR: A review of the evidence-based guidelines for the pharmacological treatment of neuropathic pain can be found in this article, where botulinum toxin, high-concentration capsaicin patch, lacosamide, selective serotonin reuptake inhibitors, and combination therapies are presented.
Journal ArticleDOI
Peripheral and central mechanisms of cutaneous hyperalgesia.
TL;DR: In the literature, there are some contradictions with respect to the stimulus modalities to which hyperalgesia and sensitization occur and this contradiction should spawn further investigations into the mechanical response properties of nociceptors and into the molecular mechanisms of heat sensitization.
Journal ArticleDOI
Neuropathic pain: An updated grading system for research and clinical practice
Nanna B. Finnerup,Simon Haroutounian,Peter R. Kamerman,Ralf Baron,David L.H. Bennett,Didier Bouhassira,Giorgio Cruccu,Roy Freeman,Per Hansson,Turo Nurmikko,Srinivasa N. Raja,Andrew S.C. Rice,Andrew S.C. Rice,Jordi Serra,Blair H. Smith,Rolf-Detlef Treede,Troels S. Jensen +16 more
TL;DR: A revised grading system of possible, probable, and definite neuropathic pain from 2008 is presented with an adjusted order, better reflecting clinical practice, improvements in the specifications, and a word of caution that even the “definite” level of neuropathicPain does not always indicate causality.