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Stacie M. Anderson

Researcher at National Institutes of Health

Publications -  104
Citations -  14543

Stacie M. Anderson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Haematopoiesis & Bone marrow. The author has an hindex of 49, co-authored 95 publications receiving 13736 citations.

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Bone marrow cells regenerate infarcted myocardium

TL;DR: It is indicated that locally delivered bone marrow cells can generate de novo myocardium, ameliorating the outcome of coronary artery disease.
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Erythrocyte P antigen: cellular receptor for B19 parvovirus

TL;DR: The pathogenic human parvovirus B19 replicates only in erythroid progenitor cells and was shown to bind to blood-group P antigen, as measured by hemagglutination, which has implications for understanding the pathogenesis of parVovirus infections and for the use ofParvoviruses in gene therapy.
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Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro

TL;DR: Anti-Fas antibody, which mimics the action of the putative ligand, enhanced IFN gamma- and TNF alpha-mediated suppression of colony formation by bone marrow (BM) in a dose-dependent manner and induced programmed cell death of CD34+ BM cells.
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Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons.

TL;DR: It is demonstrated in the hippocampus in vivo that a sizeable fraction of postnatal NG2+ progenitor cells are proliferative precursors whose progeny appears to differentiate into GABAergic neurons capable of propagating action potentials and displaying functional synaptic inputs.
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The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness.

TL;DR: Insight is provided into the requirements for persistence of T cell immune responses in the face of exhaustion and mechanisms by which effective T cell–mediated immunity may be enhanced during chronic infections and cancer are suggested.