S
Stacy Colaco
Researcher at National Institute for Research in Reproductive Health
Publications - 13
Citations - 415
Stacy Colaco is an academic researcher from National Institute for Research in Reproductive Health. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 6, co-authored 9 publications receiving 241 citations.
Papers
More filters
Journal ArticleDOI
Genetics of the human Y chromosome and its association with male infertility
Stacy Colaco,Deepak Modi +1 more
TL;DR: Screening for Yq microdeletions would aid the clinician in determining the cause of male infertility and decide a rational management strategy for the patient, as these deletions are transmitted to 100% of male offspring born through assisted reproduction, testing of Yq deletions will allow the couples to make an informed choice regarding the perpetuation ofmale infertility in future generations.
Journal ArticleDOI
Single-Cell RNA-seq Identifies Cell Subsets in Human Placenta That Highly Expresses Factors Driving Pathogenesis of SARS-CoV-2
Nancy Ashary,Anshul Bhide,Priyanka Chakraborty,Stacy Colaco,Anuradha Mishra,Karisma Chhabria,Mohit Kumar Jolly,Deepak Modi +7 more
TL;DR: The cellular targets for SARS-CoV-2 entry are uncovered and it is shown that these cells can potentially drive viremia in the developing human placenta, and the second trimester EVTs are enriched for markers of endovascular trophoblasts and the JAK-STAT pathway that drives inflammation.
Journal ArticleDOI
Paternal factors contributing to embryo quality
Stacy Colaco,Denny Sakkas +1 more
TL;DR: It is proposed that careful assessment of spermatozoal parameters is essential to achieve embryo development and a healthy live birth and the need for more research and the development of standardized protocols to assess the role of sperm factors affecting embryo quality.
Journal ArticleDOI
Consequences of Y chromosome microdeletions beyond male infertility.
Stacy Colaco,Deepak Modi +1 more
TL;DR: Observations suggest that the azoospermia factor genes may have functions beyond regulation of fertility, and this information will provide a different perspective in the area of androgenetics and have implications in devising strategies for maintaining the overall well-being of infertile males.
Posted Content
Expression of SARS-CoV-2 receptor ACE2 and the spike protein processing enzymes in developing human embryos
Stacy Colaco,Karisma Chhabria,Neha Singh,Anshul Bhide,D. V. Singh,Abhishek Kumar Singh,Atahar Husein,Anuradha Mishra,Richa Sharma,Nancy Ashary,Deepak Modi +10 more
TL;DR: The results show that developing human embryos express the receptors for SARS-CoV-2 and other coronaviruses; embryos also harbour the necessary machinery for viral internalization and replication.