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Staffan Eriksson
Researcher at Swedish University of Agricultural Sciences
Publications - 217
Citations - 7837
Staffan Eriksson is an academic researcher from Swedish University of Agricultural Sciences. The author has contributed to research in topics: Deoxycytidine kinase & Thymidine kinase. The author has an hindex of 44, co-authored 205 publications receiving 7425 citations. Previous affiliations of Staffan Eriksson include Ohio State University & Cross Cancer Institute.
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Journal ArticleDOI
Mammalian Deoxyribonucleoside Kinases
TL;DR: The physiologic metabolic role of the anabolic enzymes is discussed in relation to catabolic pathways, and alternative pathways for nucleoside analogue phosphorylation are surveyed, such as the phosphotransfer capacity of 5'-nucleotidase.
Journal ArticleDOI
Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy
TL;DR: Mutations in TK2 represent a new etiology for mitochondrial DNA depletion, underscoring the importance of the mitochondrial dNTP pool in the pathogenesis of mitochondrial depletion.
Journal ArticleDOI
The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA.
Hanna Mandel,Raymonde Szargel,Valentina Labay,Orly Elpeleg,Ann Saada,Adel Shalata,Yefim Anbinder,Drora Berkowitz,Corina Hartman,Mila Barak,Staffan Eriksson,Nadine Cohen +11 more
TL;DR: The association of mtDNA depletion with mutated DGUOK suggests that the salvage-pathway enzymes are involved in the maintenance of balanced mitochondrial dNTP pools.
Journal ArticleDOI
Structure and function of cellular deoxyribonucleoside kinases.
TL;DR: An overview of the structural studies made on this family of enzymes, including the catalytic mechanism as well as the mechanism for feedback inhibition, and homology models of other proteins in the family are made.
Journal ArticleDOI
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: The challenge ahead
William H. Goodson,Leroy Lowe,David O. Carpenter,Michael Gilbertson,Abdul Manaf Ali,Adela Lopez de Cerain Salsamendi,Ahmed Lasfar,Amancio Carnero,Amaya Azqueta,Amedeo Amedei,Amelia K Charles,Andrew Collins,Andrew Ward,Anna C. Salzberg,Annamaria Colacci,Ann-Karin Olsen,Arthur Berg,Barry J. Barclay,Binhua P. Zhou,Carmen Blanco-Aparicio,Carolyn J. Baglole,Chenfang Dong,Chiara Mondello,Chia-Wen Hsu,Christian C. Naus,Clement G. Yedjou,Colleen S. Curran,Dale W. Laird,Daniel C. Koch,Danielle J Carlin,Dean W. Felsher,Debasish Roy,Dustin G. Brown,Edward A. Ratovitski,Elizabeth P. Ryan,Emanuela Corsini,Emilio Rojas,Eun-Yi Moon,Ezio Laconi,Fabio Marongiu,Fahd Al-Mulla,Ferdinando Chiaradonna,Firouz Darroudi,Francis Martin,Frederik J. van Schooten,Gary S. Goldberg,Gerard Wagemaker,Gladys N. Nangami,Gloria M. Calaf,Gloria M. Calaf,Graeme Williams,Gregory T. Wolf,Gudrun Koppen,Gunnar Brunborg,H. Kim Lyerly,Harini Krishnan,Hasiah Ab Hamid,Hemad Yasaei,Hideko Sone,Hiroshi Kondoh,Hosni Salem,Hsue-Yin Hsu,Hyun Ho Park,Igor Koturbash,Isabelle R. Miousse,A. Ivana Scovassi,James E. Klaunig,Jan Vondráček,Jayadev Raju,Jesse Roman,Jesse Roman,John Pierce Wise,Jonathan Whitfield,Jordan Woodrick,Joseph Christopher,Josiah Ochieng,Juan Fernando Martinez-Leal,Judith Weisz,Julia Kravchenko,Jun Sun,Kalan R. Prudhomme,Kannan Badri Narayanan,Karine A. Cohen-Solal,Kim Moorwood,Laetitia Gonzalez,Laura Soucek,Le Jian,Leandro S. D'Abronzo,Liang Tzung Lin,Lin Li,Linda S M Gulliver,Lisa J. McCawley,Lorenzo Memeo,Louis Vermeulen,Luc Leyns,Luoping Zhang,Mahara Valverde,Mahin Khatami,Maria Romano,Marion Chapellier,Marc A. Williams,Mark Wade,Masoud H. Manjili,Matilde E. Lleonart,Menghang Xia,Michael J. Gonzalez,Michalis V. Karamouzis,Micheline Kirsch-Volders,Monica Vaccari,Nancy B. Kuemmerle,Nancy B. Kuemmerle,Neetu Singh,Nichola Cruickshanks,Nicole Kleinstreuer,Nik van Larebeke,Nuzhat Ahmed,Olugbemiga Ogunkua,Periyadan K. Krishnakumar,Pankaj Vadgama,Paola A. Marignani,Paramita M. Ghosh,Patricia Ostrosky-Wegman,Patricia A. Thompson,Paul Dent,Petr Heneberg,Philippa D. Darbre,Po Sing Leung,Pratima Nangia-Makker,Qiang Shawn Cheng,R. Brooks Robey,R. Brooks Robey,Rabeah Al-Temaimi,Rabindra Roy,Rafaela Andrade-Vieira,Ranjeet Kumar Sinha,Rekha Mehta,Renza Vento,Renza Vento,Riccardo Di Fiore,Richard Ponce-Cusi,Rita Dornetshuber-Fleiss,Rita Dornetshuber-Fleiss,Rita Nahta,Robert C. Castellino,Roberta Palorini,Roslida Abd Hamid,Sabine A. S. Langie,Sakina E. Eltom,Samira A. Brooks,Sandra Ryeom,Sandra S. Wise,Sarah N Bay,Shelley A. Harris,Shelley A. Harris,Silvana Papagerakis,Simona Romano,Sofia Pavanello,Staffan Eriksson,Stefano Forte,Stephanie C. Casey,Sudjit Luanpitpong,Tae-Jin Lee,Takemi Otsuki,Tao Chen,Thierry Massfelder,Thomas Sanderson,Tiziana Guarnieri,Tove Hultman,Valérian Dormoy,Valérian Dormoy,Valerie Odero-Marah,Venkata S. Sabbisetti,Véronique Maguer-Satta,W. Kimryn Rathmell,Wilhelm Engström,William K. Decker,William H. Bisson,Yon Rojanasakul,Yunus A. Luqmani,Zhenbang Chen,Zhiwei Hu +180 more
TL;DR: Low-dose exposures to common environmental chemicals that are deemed safe individually may be combining to instigate carcinogenesis, thereby contributing to the incidence of cancer.