Stavros Bashiardes

TL;DR: The metagenomically characterized the murine and human mucosal-associated gastrointestinal microbiome and found it to only partially correlate with stool microbiome, indicating that empiric probiotics supplementation may be limited in universally and persistently impacting the gut mucosa.

TL;DR: Collectively, potential post-antibiotic probiotic benefits may be offset by a compromised gut mucosal recovery, highlighting a need of developing aFMT or personalized probiotic approaches achieving mucosal protection without compromising microbiome recolonization in the antibiotics-perturbed host.

TL;DR: It is demonstrated that Akkermansia muciniphila (AM) ameliorates whereas Ruminococcus torques and Parabacteroides distasonis exacerbate the symptoms of ALS, and it is suggested that environmentally driven microbiome–brain interactions may modulate ALS in mice.

TL;DR: Some of the key metatranscriptomics strategies that are implemented to determine microbiota gene expression and its regulation are highlighted and discussed and the advantages and potential challenges associated with these approaches are discussed.

TL;DR: Current understanding of immune-metabolism interactions is highlighted, differences among individuals and between populations in this respect are illustrated, and future avenues of research possibly enabling immune harnessing as means of personalized treatment for common metabolic disorders are pointed toward.