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Stefan Leucht
Researcher at Technische Universität München
Publications - 512
Citations - 41377
Stefan Leucht is an academic researcher from Technische Universität München. The author has contributed to research in topics: Antipsychotic & Randomized controlled trial. The author has an hindex of 94, co-authored 446 publications receiving 34746 citations. Previous affiliations of Stefan Leucht include Centre for Addiction and Mental Health & Hospital for Sick Children.
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Journal ArticleDOI
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis
Stefan Leucht,Andrea Cipriani,Andrea Cipriani,Loukia M. Spineli,Dimitris Mavridis,Deniz Örey,Franziska Richter,Myrto Samara,Corrado Barbui,Rolf R. Engel,John R. Geddes,Werner Kissling,Marko Paul Stapf,Bettina Lässig,Georgia Salanti,John M. Davis +15 more
TL;DR: A Bayesian-framework, multiple-treatments meta-analysis of randomised controlled trials to compare 15 antipsychotic drugs and placebo in the acute treatment of schizophrenia found all drugs were significantly more effective than placebo.
Journal ArticleDOI
Physical illness in patients with severe mental disorders.I. Prevalence, impact of medications and disparities in health care
Marc De Hert,Christoph U. Correll,Julio Bobes,Marcelo Cetkovich-Bakmas,Dan Cohen,Itsuo Asai,Johan Detraux,S. Gautam,Hans-Jurgen Möller,David M. Ndetei,John W. Newcomer,Richard Uwakwe,Stefan Leucht +12 more
TL;DR: Prevalence rates of different physical illnesses as well as important individual lifestyle choices, side effects of psychotropic treatment and disparities in health care access, utilization and provision that contribute to these poor physical health outcomes are reported.
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Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis
Andrea Cipriani,Andrea Cipriani,Toshi A. Furukawa,Georgia Salanti,Anna Chaimani,Anna Chaimani,Anna Chaimani,Lauren Z Atkinson,Lauren Z Atkinson,Yusuke Ogawa,Stefan Leucht,Henricus G. Ruhé,Henricus G. Ruhé,Erick H. Turner,Julian P T Higgins,Matthias Egger,Nozomi Takeshima,Yu Hayasaka,Hissei Imai,Kiyomi Shinohara,Aran Tajika,John P. A. Ioannidis,John R. Geddes,John R. Geddes +23 more
TL;DR: This work aimed to update and expand previous work to compare and rank antidepressants for the acute treatment of adults with unipolar major depressive disorder, and found that all antidepressants were more effective than placebo.
Journal ArticleDOI
Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis
Stefan Leucht,Caroline Corves,Caroline Corves,Dieter Arbter,Rolf R. Engel,Chunbo Li,Chunbo Li,John M. Davis +7 more
TL;DR: A meta-analysis of randomised controlled trials to compare the effects of second-generation antipsychotic drugs in patients with schizophrenia provided data for individualised treatment based on efficacy, side-effects, and cost.
Journal ArticleDOI
What does the PANSS mean
Stefan Leucht,Stefan Leucht,John M. Kane,Werner Kissling,Johannes Hamann,Eva Etschel,Rolf R. Engel +6 more
TL;DR: The results provide a better framework for understanding the clinical meaning of the PANSS total score in drug trials of schizophrenia patients with acute exacerbations and may ideally use at least a 50% reduction from baseline cut-off to define response rather than lower thresholds.