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Stefan Osswald

Researcher at University Hospital of Basel

Publications -  418
Citations -  16217

Stefan Osswald is an academic researcher from University Hospital of Basel. The author has contributed to research in topics: Atrial fibrillation & Myocardial infarction. The author has an hindex of 60, co-authored 366 publications receiving 13607 citations. Previous affiliations of Stefan Osswald include University of Basel & Harvard University.

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Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy

Christian Templin, +68 more
TL;DR: Patients with takotsubo cardiomyopathy had a higher prevalence of neurologic or psychiatric disorders than did those with an acute coronary syndrome and physical triggers, acute neurologics or psychiatric diseases, high troponin levels, and a low ejection fraction on admission were independent predictors for in-hospital complications.
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Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents.

TL;DR: After the discontinuation of clopidogrel, the benefit of DES in reducing target vessel revascularization is maintained but has to be balanced against an increase in late cardiac death or nonfatal MI, possibly related to late stent thrombosis.
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One-Hour Rule-out and Rule-in of Acute Myocardial Infarction Using High-Sensitivity Cardiac Troponin T

TL;DR: Using a simple algorithm incorporating hs-cTnT baseline values and absolute changes within the first hour allowed a safe rule-out as well as an accurate rule-in of AMI within 1 hour in 77% of unselected patients with acute chest pain.
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Utility of Absolute and Relative Changes in Cardiac Troponin Concentrations in the Early Diagnosis of Acute Myocardial Infarction

TL;DR: Absolute changes of cTn levels have a significantly higher diagnostic accuracy for AMI than relative changes, and seem to be the preferred criteria to distinguish AMI from other causes ofcTn elevations.
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Incremental cost-effectiveness of drug-eluting stents compared with a third-generation bare-metal stent in a real-world setting: randomised Basel Stent Kosten Effektivitäts Trial (BASKET).

TL;DR: In a real-world setting, use of DES in all patients is less cost effective than in studies with selected patients, and use of these stents could be restricted to patients in high-risk groups.