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Stefania Bruno
Researcher at University of Turin
Publications - 128
Citations - 15592
Stefania Bruno is an academic researcher from University of Turin. The author has contributed to research in topics: Stem cell & Mesenchymal stem cell. The author has an hindex of 51, co-authored 116 publications receiving 13277 citations. Previous affiliations of Stefania Bruno include Health Science University & Fresenius Medical Care.
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Journal ArticleDOI
Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury
Stefania Bruno,Cristina Grange,Maria Chiara Deregibus,Raffaele A. Calogero,Silvia Saviozzi,Federica Collino,Laura Morando,Alessandro Busca,Michele Falda,Benedetta Bussolati,Ciro Tetta,Giovanni Camussi +11 more
TL;DR: It is found that microvesicles derived from human bone marrow MSCs stimulated proliferation in vitro and conferred resistance of tubular epithelial cells to apoptosis, suggesting RNA-dependent biologic effects.
Journal ArticleDOI
Exosomes/microvesicles as a mechanism of cell-to-cell communication
TL;DR: The transfer of gene products from injured cells may explain stem cell functional and phenotypic changes without the need of transdifferentiation into tissue cells, and the evidence supporting a bidirectional exchange of genetic information between stem and injured cells is discussed.
Journal ArticleDOI
Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study.
Aravinthan Varatharaj,Aravinthan Varatharaj,Naomi Thomas,Mark Ellul,Mark Ellul,Mark Ellul,Nicholas W. S. Davies,Thomas A Pollak,Elizabeth L Tenorio,Mustafa Sultan,Ava Easton,Gerome Breen,Michael S. Zandi,Jonathan P. Coles,Hadi Manji,Rustam Al-Shahi Salman,David K. Menon,Timothy R Nicholson,Laura A Benjamin,Laura A Benjamin,Alan Carson,Craig J. Smith,Martin R Turner,Tom Solomon,Tom Solomon,Tom Solomon,Rachel Kneen,Rachel Kneen,Sarah Pett,Ian Galea,Ian Galea,Rhys H. Thomas,Rhys H. Thomas,Benedict D Michael,Benedict D Michael,Benedict D Michael,Claire Allen,Neil Archibald,James Arkell,Peter Arthur-Farraj,Mark R. Baker,Harriet A. Ball,Verity Bradley-Barker,Zoe Brown,Stefania Bruno,Lois Carey,Christopher Carswell,Annie Chakrabarti,James Choulerton,Mazen Daher,Ruth Davies,Rafael Di Marco Barros,Sofia Dima,Rachel Dunley,Dipankar Dutta,Richard James Booth Ellis,Alex Everitt,Joseph Fady,Patricia Fearon,Leonora Fisniku,Ivie Gbinigie,Alan Gemski,Emma Gillies,Effrossyni Gkrania-Klotsas,Julie Grigg,Hisham Hamdalla,Jack Hubbett,Neil Hunter,Anne-Catherine Huys,Ihmoda Ihmoda,Sissi Ispoglou,Ashwani Jha,Ramzi Joussi,Dheeraj Kalladka,Hind Khalifeh,Sander Kooij,Guru Kumar,Sandar Kyaw,Lucia Li,Edward Littleton,Malcolm R. Macleod,Mary Joan MacLeod,Barbara Madigan,Vikram Mahadasa,Manonmani Manoharan,Richard Marigold,Isaac Marks,Paul M. Matthews,Michael Mccormick,Caroline Mcinnes,Antonio Metastasio,Philip Milburn-McNulty,Clinton Mitchell,Duncan Mitchell,Clare Morgans,Huw R. Morris,Jasper M. Morrow,Ahmed Mubarak Mohamed,Paula Mulvenna,Louis Murphy,Robert Namushi,Edward J Newman,Wendy Phillips,Ashwin Pinto,David A Price,Harald Proschel,Terry Quinn,Deborah Ramsey,Christine Roffe,Amy L Ross Russell,Neshika Samarasekera,Stephen Sawcer,Walee Sayed,Lakshmanan Sekaran,Jordi Serra-Mestres,Victoria K. Snowdon,Gayle Strike,James Sun,Christina Tang,Mark Vrana,Ryckie G. Wade,Chris Wharton,Lou Wiblin,Iryna Boubriak,Katie Herman,Gordon T. Plant +125 more
TL;DR: This is the first nationwide, cross-specialty surveillance study of acute neurological and psychiatric complications of COVID-19 and provides valuable and timely data that are urgently needed by clinicians, researchers, and funders.
Journal ArticleDOI
Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA.
Maria Chiara Deregibus,Vincenzo Cantaluppi,Raffaele A. Calogero,Marco Lo Iacono,Ciro Tetta,Luigi Biancone,Stefania Bruno,Benedetta Bussolati,Giovanni Camussi +8 more
TL;DR: Protein expression and functional studies showed that PI3K and eNOS play a critical role in the angiogenic effect of MVs, suggesting that EPCs may activate angiogenesis in endothelial cells by releasing MVs able to trigger an angiogens program.
Journal ArticleDOI
Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury
Stefano Gatti,Stefania Bruno,Maria Chiara Deregibus,Andrea Sordi,Vincenzo Cantaluppi,Ciro Tetta,Giovanni Camussi +6 more
TL;DR: It is found that a single administration of MVs, immediately after IRI, protects rats from AKI by inhibiting apoptosis and stimulating tubular epithelial cell proliferation, and suggests that MVs could be exploited as a potential new therapeutic approach.