S
Stephan Christgai
Researcher at University of California, San Francisco
Publications - 1
Citations - 1522
Stephan Christgai is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Glutamate decarboxylase. The author has an hindex of 1, co-authored 1 publications receiving 1488 citations.
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Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase.
Steinunn Baekkeskov,Henk-Jan Aanstoot,Stephan Christgai,Annette Reetz,Michele Solimena,Marilia Cascalho,Franco Folli,Hanne Richter-Olesen,Pietro De Camilli +8 more
TL;DR: The pancreatic islet β-cell autoantigen of relative molecular mass 64,000 (64K), which is a major target of autoantibodies associated with the development of insulin-dependent diabetes mel-litus (IDDM), has been identified as glutamic acid decarboxylase, the biosynthesizing enzyme of the inhibitory neurotransmitter GABA.