S
Stéphane Bach
Researcher at Centre national de la recherche scientifique
Publications - 102
Citations - 4294
Stéphane Bach is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Lithium & Kinase. The author has an hindex of 33, co-authored 90 publications receiving 4002 citations. Previous affiliations of Stéphane Bach include Chimie ParisTech & North-West University.
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Journal ArticleDOI
Raman spectra of birnessite manganese dioxides
Christian M. Julien,M. Massot,Rita Baddour-Hadjean,Sylvain Franger,Stéphane Bach,Jean-Pierre Pereira-Ramos +5 more
TL;DR: In this article, the structural features of layered manganese dioxides of the Birnessite family were studied using Raman scattering spectroscopy, which is capable of analysing directly the near-neighbour environment of oxygen coordination around menganese and lithium cations.
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Roscovitine Targets, Protein Kinases and Pyridoxal Kinase
Stéphane Bach,Marie Knockaert,Jens Reinhardt,Olivier Lozach,Sophie Schmitt,Blandine Baratte,Marcel Koken,Stephen P. Coburn,Lin Tang,Tao Jiang,Dong-Cai Liang,Hervé Galons,Jean-Francois Dierick,Lorenzo A. Pinna,Flavio Meggio,Frank Totzke,Christoph Schächtele,Andrea S. Lerman,Amancio Carnero,Yongqin Wan,Nathanael S. Gray,Laurent Meijer +21 more
TL;DR: The results show that (R)-roscovitine is rather selective for CDKs, in fact most kinases are not affected, but it binds an unexpected, non-protein kinase target, pyridoxal kinase, the enzyme responsible for phosphorylation and activation of vitamin B6.
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Sol-gel synthesis of manganese oxides
TL;DR: Transparent and stable manganese dioxide gels are obtained upon reduction of permanganate aqueous solutions AMnO4 [A = Li, Na, K, NH4, N(CH3)4] by fumaric acid as discussed by the authors.
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Isolation of drugs active against mammalian prions using a yeast-based screening assay
Stéphane Bach,Nicolas Talarek,Thibault Andrieu,Jean-Michel Vierfond,Yvette Mettey,Hervé Galons,Dominique Dormont,Laurent Meijer,Christophe Cullin,Marc Blondel +9 more
TL;DR: Results validate the present method as an efficient high-throughput screening approach to identify new prion inhibitors and suggest that biochemical pathways controlling prion formation and/or maintenance are conserved from yeast to humans.
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The BRET technology and its application to screening assays.
TL;DR: The original BRET‐based methodology, more recent variants, and potential applications to drug screening are described.