S
Stéphane Doly
Researcher at French Institute of Health and Medical Research
Publications - 46
Citations - 2390
Stéphane Doly is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Serotonin & Receptor. The author has an hindex of 25, co-authored 42 publications receiving 2201 citations. Previous affiliations of Stéphane Doly include Paris Descartes University & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
A population-specific htr2b stop codon predisposes to severe impulsivity
Laura Bevilacqua,Stéphane Doly,Jaakko Kaprio,Jaakko Kaprio,Qiaoping Yuan,Roope Tikkanen,Tiina Paunio,Zhifeng Zhou,Juho Wedenoja,Juho Wedenoja,Luc Maroteaux,Silvina L. Diaz,Arnauld Belmer,Colin A. Hodgkinson,Liliana Dell'Osso,Jaana Suvisaari,Emil F. Coccaro,Richard J. Rose,Leena Peltonen,Matti Virkkunen,David Goldman +20 more
TL;DR: In this paper, a stop codon in HTR2B was identified that is common (minor allele frequency > 1%) but exclusive to Finnish people, which was associated with psychiatric diseases marked by impulsivity in both population and family-based analyses.
A population-specific HTR2B stop codon predisposes to severe impulsivity
Laura Bevilacqua,Stéphane Doly,Jaakko Kaprio,Jaakko Kaprio,Qiaoping Yuan,Roope Tikkanen,Tiina Paunio,Zhifeng Zhou,Juho Wedenoja,Juho Wedenoja,Luc Maroteaux,Silvina L. Diaz,Arnauld Belmer,Colin A. Hodgkinson,Liliana Dell'Osso,Jaana Suvisaari,Emil F. Coccaro,Richard J. Rose,Leena Peltonen,Matti Virkkunen,David Goldman +20 more
TL;DR: In this paper, a stop codon in HTR2B was identified that is common (minor allele frequency > 1%) but exclusive to Finnish people, which was associated with psychiatric diseases marked by impulsivity in both population and family-based analyses.
Journal ArticleDOI
5-HT 2B receptors are required for serotonin-selective antidepressant actions
Silvina L. Diaz,Stéphane Doly,Stéphane Doly,Nicolas Narboux-Nême,Nicolas Narboux-Nême,Sebastian P. Fernandez,Sebastian P. Fernandez,P. Mazot,P. Mazot,Sophie Marie Banas,Sophie Marie Banas,Katia Boutourlinsky,Katia Boutourlinsky,Imane Moutkine,Imane Moutkine,Arnauld Belmer,Arnauld Belmer,Anne Roumier,Anne Roumier,Luc Maroteaux,Luc Maroteaux +20 more
TL;DR: The 5-HT2B receptor appears to positively modulate serotonergic activity and to be required for the therapeutic actions of SSRIs, and should be considered as a new tractable target in the combat against depression.
Journal ArticleDOI
Serotonin 5-HT2B Receptors Are Required for 3,4-Methylenedioxymethamphetamine-Induced Hyperlocomotion and 5-HT Release In Vivo and In Vitro
Stéphane Doly,Emmanuel Valjent,Vincent Setola,Jacques Callebert,Denis Hervé,Jean-Marie Launay,Luc Maroteaux +6 more
TL;DR: These findings reveal a novel regulatory component in the actions of MDMA and represent the first demonstration that 5-HT2B receptors play an important role in the brain, i.e., modulation of 5- HT release, and may serve as promising therapeutic drugs for MDMA abuse.
5-HT(2B) receptors are required for serotonin-selective antidepressant actions
Silvina L. Diaz,Stéphane Doly,Stéphane Doly,Nicolas Narboux-Nême,Nicolas Narboux-Nême,Sebastian P. Fernandez,Sebastian P. Fernandez,P. Mazot,P. Mazot,Sophie Marie Banas,Sophie Marie Banas,Katia Boutourlinsky,Katia Boutourlinsky,Imane Moutkine,Imane Moutkine,Arnauld Belmer,Arnauld Belmer,Anne Roumier,Anne Roumier,Luc Maroteaux,Luc Maroteaux +20 more
TL;DR: The 5-HT(2B) receptor appears to positively modulate serotonergic activity and to be required for the therapeutic actions of SSRIs in the combat against depression as mentioned in this paper.