Stéphane Laurent

TL;DR: It is suggested for the first time that, in humans, hypertension may act on the arterial wall not only through the amplitude of peak systolic and end-diastolic blood pressure but also through several other mechanical factors involving the level of pulse pressure and heart rate and also blood pressure variability.

TL;DR: In Williams syndrome patients, the carotid artery wall was abnormally distensible and thick, and major ultrastructural abnormalities of elastic fibres were observed in association with smooth muscle cell de-differentiation, indicating that the haplo-insufficiency of the elastin gene in WS patients leads to abnormal elastic fibre assembly within the media.

TL;DR: In a middle-aged cohort with high prevalence of hypertension cPP is more closely correlated with cardiovascular phenotypes than pPP, however, cPP does not provide additional information beyond pPP when adjusted for relevant cofactors.

TL;DR: The SPARTE study as discussed by the authors showed that a carotid-femoral pulse wave velocity (PWV) measured every 6 months can significantly reduce office and ambulatory systolic blood pressure.

TL;DR: Findings indicate that the longitudinal mechanics of "complex" plaques follows a specific pattern of reduced strain and suggest that reduced strain, associated with an outer remodeling, may be a feature of high-risk plaques.