Stephanie M. Halmo

TL;DR: This review will focus on recent discoveries delineating the various enzymes, structures and functions associated with O-mannose-initiated glycoproteins, and discusses the evolution of this pathway.

TL;DR: This in vitro method allowed us to validate the sugar-nucleotide donor-substrate specificities of recombinantly expressed human, bovine, bacterial and protozoan GTs and should facilitate discovery of novel GTs that participate in diverse biological processes.

TL;DR: These findings begin to define the selectivity of POMGNT2 and suggest that this enzyme functions as a gatekeeper enzyme to prevent the vast majority of O-mannosylated sites on proteins from becoming modified with glycan structures functional for binding laminin globular domain-containing proteins.

TL;DR: It is revealed that students used domain‐general and domain‐specific knowledge in their problem solving, and difficulties for students with the amino acid backbone, amino acid categorization, and causal mechanisms of noncovalent interactions are identified.

TL;DR: This study investigated the impact of worked examples plus practice, productive failure, and two forms of guided inquiry on student learning of a foundational concept in biochemistry and showed that the four pedagogies did not differentially impact basic knowledge performance.