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Stephen B. H. Kent
Researcher at University of Chicago
Publications - 343
Citations - 41215
Stephen B. H. Kent is an academic researcher from University of Chicago. The author has contributed to research in topics: Chemical synthesis & Native chemical ligation. The author has an hindex of 87, co-authored 341 publications receiving 39885 citations. Previous affiliations of Stephen B. H. Kent include University of Auckland & Chiron Corporation.
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PatentDOI
Synthesis of proteins by native chemical ligation
TL;DR: The technique of native chemical ligation is employable for chemically synthesizing full length proteins as discussed by the authors, which are chemically identical to proteins produced by cell free synthesis, and can be refolded and/or oxidized to form native disulfide-containing protein molecules.
Journal ArticleDOI
Composite Quasar Spectra from the Sloan Digital Sky Survey
Daniel E. Vanden Berk,Gordon T. Richards,Amanda E. Bauer,Michael A. Strauss,Donald P. Schneider,Timothy M. Heckman,Donald G. York,Patrick B. Hall,Patrick B. Hall,Xiaohui Fan,Gillian R. Knapp,Scott F. Anderson,James Annis,Neta A. Bahcall,Mariangela Bernardi,John W. Briggs,Jon Brinkmann,Robert J. Brunner,Scott Burles,Larry N. Carey,Francisco J. Castander,Francisco J. Castander,A. J. Connolly,James H. Crocker,István Csabai,István Csabai,Mamoru Doi,Douglas P. Finkbeiner,Scott D. Friedman,Joshua A. Frieman,Joshua A. Frieman,Masataka Fukugita,James E. Gunn,Gregory S. Hennessy,Željko Ivezić,Stephen B. H. Kent,Stephen B. H. Kent,Peter Z. Kunszt,D. Q. Lamb,R. French Leger,Dan Long,Jon Loveday,Robert H. Lupton,Avery Meiksin,Aronne Merelli,Aronne Merelli,Jeffrey A. Munn,Heidi Jo Newberg,M. Newcomb,Robert C. Nichol,Russell Owen,Jeffrey R. Pier,Adrian Pope,Adrian Pope,Constance M. Rockosi,David J. Schlegel,Walter A. Siegmund,Stephen A. Smee,Stephen A. Smee,Yehuda Snir,Chris Stoughton,Christopher W. Stubbs,Mark SubbaRao,Alexander S. Szalay,Gyula P. Szokoly,Christy Tremonti,Alan Uomoto,Patrick Waddell,Brian Yanny,Wei Zheng +69 more
TL;DR: In this article, a variety of composite quasar spectra using a homogeneous data set of over 2200 spectra from the Sloan Digital Sky Survey (SDSS) was created, and the median composite covers a restwavelength range from 800 to 8555 A and reaches a peak signal-to-noise ratio of over 300 per 1 A resolution element in the rest frame.
Journal ArticleDOI
Fluorescence detection in automated DNA sequence analysis
Lloyd M. Smith,Jane Z. Sanders,Robert J. Kaiser,Peter Hughes,Chris Dodd,Charles R. Connell,Cheryl Heiner,Stephen B. H. Kent,Leroy Hood +8 more
TL;DR: A method for the partial automation of DNA sequence analysis by means of a fluorophore covalently attached to the oligonucleotide primer used in enzymaticDNA sequence analysis.
Journal ArticleDOI
A cellular gene encodes scrapie PrP 27-30 protein
Bruno Oesch,Bruno Oesch,David Westaway,Monika Wälchli,Monika Wälchli,Michael P. McKinley,Stephen B. H. Kent,Stephen B. H. Kent,Ruedi Aebersold,Ruedi Aebersold,Ronald A. Barry,Paul Tempst,Paul Tempst,David B. Teplow,David B. Teplow,Leroy Hood,Leroy Hood,Stanley B. Prusiner,Stanley B. Prusiner,Charles Weissmann,Charles Weissmann +20 more
TL;DR: A clone encoding PrP 27-30, the major protein in purified preparations of scrapie agent, was selected from a scrapie-infected hamster brain cDNA library by oligonucleotide probes corresponding to the N terminus of the protein.
Journal ArticleDOI
Efficient method for the preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis
TL;DR: In this article, the authors present an automated solid-phase method for the synthesis of oligo(N-substituted glycines) (NSGs) which is general for a wide variety of side-chain substituents and allows the rapid synthesis of molecules of potential therapeutic interest.