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Stephen B. Harrap
Researcher at University of Melbourne
Publications - 264
Citations - 22406
Stephen B. Harrap is an academic researcher from University of Melbourne. The author has contributed to research in topics: Blood pressure & Diabetes mellitus. The author has an hindex of 56, co-authored 255 publications receiving 20672 citations. Previous affiliations of Stephen B. Harrap include Federation University Australia & University of Calgary.
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Journal ArticleDOI
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.
Anushka Patel,Stephen MacMahon,John Chalmers,Bruce Neal,Laurent Billot,Mark Woodward,Mark Woodward,Michel Marre,Mark E. Cooper,Paul Glasziou,Paul Glasziou,Diederick E. Grobbee,Pavel Hamet,Stephen B. Harrap,Simon Heller,Lisheng Liu,Giuseppe Mancia,Carl Erik Mogensen,C. Y. Pan,Neil R Poulter,Anthony Rodgers,Bryan Williams,Severine Bompoint,Bastiaan E. de Galan,Bastiaan E. de Galan,Rohina Joshi,F. Travert +26 more
TL;DR: A strategy of intensive glucose control, involving gliclazide (modified release) and other drugs as required, that lowered the glycated hemoglobin value to 6.5% yielded a 10% relative reduction in the combined outcome of major macrovascular and microvascular events, primarily as a consequence of a 21%relative reduction in nephropathy.
Journal ArticleDOI
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack
Stephen MacMahon,Bruce Neal,Christophe Tzourio,Anthony Rodgers,Mark Woodward,J. Cutler,Craig S. Anderson,John Chalmers,T. Ohkubo,M. G. Bouser,Stephen M. Davis,Geoffrey A. Donnan,L. Hansson,Stephen B. Harrap,K. R. Lees,L. Liu,G. Mancia,T. Omae,J. Reid,R. Sega,A. Terent,C. Warlow,N. Anderson,C. Bladin,B.C. Chambers,G. Gordon,N. Sharpe,Rory Collins,Peter Sandercock,John Simes,P. Sleight,A. Brnabic,S. Colman,L. Francis,A. Lee,L. Gong,M.-G. Bousser,T. Yamaguchi,F. William,Q. Deng,D. X. Hu,William Y.S. Wang,A. L. Wu,L. Y. Ma,Z. Y. Tao,V. Biousse,Karine Berthet,L. Ben Slamia,C. Le Denmat,S. Crespi,G. Foglia,C. Fujimoto,S. Matsumura,K. Marttala,M. Pettersson,M. Safwenberg,J. Fenton,Y. McIlvenna,R. Currie,H. Bartram,J. Briad,A. Clague,Y. Cleverly,M. Cosson,A. Culpan,D. Douglas,S. Flett,B. Gray,T. Holloway,A. Milne,R. Prasad,Y. Ratnasabapathy,A. Santos,M. Wills,T. Agnew,Neil Chapman,N. Lewis,B. Mullane +77 more
TL;DR: This blood-pressure-lowering regimen reduced the risk of stroke among both hypertensive and non-hypertensive individuals with a history of stroke or transient ischaemic attack, irrespective of their blood pressure.
Journal ArticleDOI
Clinical practice guidelines for the management of hypertension in the community a statement by the american society of hypertension and the international society of hypertension
Michael A. Weber,Ernesto L. Schiffrin,William B. White,Samuel J. Mann,Lars H Lindholm,John Kenerson,John M. Flack,Barry L. Carter,Barry J. Materson,C Venkata S Ram,Debbie L. Cohen,Jean Claude Cadet,Roger R. Jean-Charles,Sandra J. Taler,David S. Kountz,Raymond R. Townsend,John Chalmers,Agustin J. Ramirez,George L. Bakris,Jiguang Wang,Aletta E. Schutte,John D. Bisognano,Rhian M. Touyz,D Sica,Stephen B. Harrap +24 more
TL;DR: Clinical Practice Guidelines for the Management of Hypertension in the Community as mentioned in this paper A Statement by the American Society of hypertension and the International Society of Hyperpharmension (ISH).
Journal ArticleDOI
Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension.
Michael A. Weber,Ernesto L. Schiffrin,William B. White,Samuel J. Mann,Lars H Lindholm,John Kenerson,John M. Flack,Barry L. Carter,Barry J. Materson,C Venkata S Ram,Debbie L. Cohen,Jean Claude Cadet,Roger R. Jean-Charles,Sandra J. Taler,David S. Kountz,Raymond R. Townsend,John Chalmers,Agustin J. Ramirez,George L. Bakris,Jiguang Wang,Aletta E. Schutte,John D. Bisognano,Rhian M. Touyz,D Sica,Stephen B. Harrap +24 more
TL;DR: Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of hypertension as mentioned in this paper, which is based on guidelines from the National Institute of Neurological Disorders and Strochastic Hemorrhage.
Journal ArticleDOI
Follow-up of Blood-Pressure Lowering and Glucose Control in Type 2 Diabetes
Sophia Zoungas,John Chalmers,Bruce Neal,Laurent Billot,Qiang Li,Yoichiro Hirakawa,Hisatomi Arima,Helen Monaghan,Rohina Joshi,Stephen Colagiuri,Mark E. Cooper,Paul Glasziou,Diederick E. Grobbee,Pavel Hamet,Stephen B. Harrap,Simon Heller,Liu Lisheng,Giuseppe Mancia,Michel Marre,David R. Matthews,Carl Erik Mogensen,Vlado Perkovic,Neil Poulter,Anthony Rodgers,Bryan Williams,Stephen MacMahon,Anushka Patel,Mark Woodward +27 more
TL;DR: There was no evidence that intensive glucose control during the ADVANCE factorial trial led to long-term benefits with respect to mortality or macrovascular events.