S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Genome-wide and differential proteomic analysis of hepatitis B virus and aflatoxin B1 related hepatocellular carcinoma in Guangxi, China.
Lu-Nan Qi,Le-Qun Li,Yuan-Yuan Chen,Zhao-hong Chen,Tao Bai,Bang-De Xiang,Xiao Qin,Kaiyin Xiao,Minhao Peng,Zhi-Ming Liu,Tang-Wei Liu,Xue Qin,Shan Li,Ze-Guang Han,Zengnan Mo,Regina M. Santella,Cheryl A. Winkler,Stephen J. O'Brien,Tao Peng +18 more
TL;DR: A number of genetic and gene expression alterations were found to be associated with HBV and AFB1- related HCC, and a significant correlation between the expression of AKR 1B10 mRNA and protein levels as well as AKR1B10 copy number was observered, which suggest that AKR2B10 may play a role in AFB2-related hepatocarcinogenesis.
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A gene (Bevi) on human chromosome 6 is an integration site for baboon type C DNA provirus in human cells
TL;DR: The results confirmed that a gene, Bevi, previously assigned to human chromosome 6, dominantly controls baboon type C virus expression in hybrid cells, and concluded that Bevi is a preferred integration site for the baboontype C provirus in the human genome.
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Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survival.
Sher L. Hendrickson,Lisa P. Jacobson,George W. Nelson,John P. Phair,James A. Lautenberger,Randall C. Johnson,Lawrence A. Kingsley,Joseph B. Margolick,Roger Detels,James J. Goedert,Stephen J. O'Brien +10 more
TL;DR: ARG influence after HAART suggests residual HIV-1 replication, and spread continues even in patients successfully suppressing detectable viral RNA.
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African horse sickness and African carnivores
Kathleen A. Alexander,Pieter W. Kat,James A. House,Carol House,Stephen J. O'Brien,M. K. Laurenson,J. W. Mcnutt,Bennie Osburn +7 more
TL;DR: Evidence of widespread natural AHS infection among a diversity of African carnivore species is presented, and it is hypothesize that such infection resulted from ingestion of meat and organs from AHS-infected prey species.
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Analysis of multiple isoenzyme expression among twenty-two species of Mycoplasma and Acholeplasma.
TL;DR: Mycoplasma-specific enzymes found in infected-cell extracts had the same electrophoretic mobility patterns as enzymes obtained from broth-grown mycoplasmas of the same species.