S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Mitochondrial Haplogroups Are Associated With Risk of Neuroretinal Disorder in HIV-Positive Patients
Sher L. Hendrickson,Douglas A. Jabs,Mark L. Van Natta,Richard A. Lewis,Douglas C. Wallace,Stephen J. O'Brien +5 more
TL;DR: It is suggested that mitochondrial genotype may influence propensity to develop HIV-associated NRD in patients with AIDS and an independent association with protection against NRD is suggested in a cross-section of all patients taken at enrollment.
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Evolution of the Male-Determining Gene SRY Within the Cat Family Felidae
V. King,P. N. Goodfellow,A. J. Pearks Wilkerson,Warren E. Johnson,Stephen J. O'Brien,Jill Pecon-Slattery +5 more
TL;DR: Comparative genomic analyses of SRY along with the adjacent noncoding 5′ flank and 3′ flank in 36 species of the cat family Felidae indicate that the nonc coding genomic flanks and SRY closely track species divergence, however, several inconsistencies are observed in SRY.
Journal Article
Validation of a short tandem repeat multiplex typing system for genetic individualization of domestic cat samples.
TL;DR: The cat STR multiplex typing system is a robust and reliable tool for the use of forensic DNA analysis of domestic cat samples and confirms that the multiplex system was species-specific for feline DNA and amplified robustly with as little as 125 picograms of genomic template DNA, demonstrating good product balance.
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The use of a posterior lip augmentation device for a revision of recurrent dislocation after primary cemented Charnley/Charnley Elite total hip replacement
TL;DR: Between April 1992 and July 2005, 310 posterior lip augmentation devices were used for the treatment of recurrent dislocation of the hip in 307 patients who had received primary total hip replacements using Charnley/Charnley Elite components with a cemented acetabulum.
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Chromosome assignment by polymerase chain reaction techniques: assignment of the oncogene FGF-5 to human chromosome 4.
TL;DR: A new chromosomal assignment method based on the polymerase chain reaction mediated amplification of target sequences in DNAs from somatic cell hybrids is described, which is faster, much more sensitive and less labor intensive than the standard method of chromosome assignment by Southern hybridization analysis of Somatic cell hybrid DNAs.