S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
The Ancestral Carnivore Karyotype (2n = 38) Lives Today in Ringtails
William G. Nash,Joan C. Menninger,Hesed Padilla-Nash,Gary Stone,Polina L. Perelman,Stephen J. O'Brien +5 more
TL;DR: The patterns of chromosome segment homology among Carnivore species allowed us to reconstruct and propose the disposition of a high-resolution banded ancestral carnivore karyotype (ACK), suggesting that the ACK chromosome number would be 38, rather than the previously supposed 42.
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Association of Host Genetic Risk Factors With the Course of Cytomegalovirus Retinitis in Patients Infected With Human Immunodeficiency Virus
Efe Sezgin,Mark L. Van Natta,Alka Ahuja,Alice T. Lyon,Sunil K. Srivastava,Jennifer L. Troyer,Stephen J. O'Brien,Douglas A. Jabs,Douglas A. Jabs +8 more
TL;DR: Besides overall immune health, host genetic factors influence mortality, retinitis progression, and retinal detachment in patients with AIDS and CMV retinopathy that are receiving HAART.
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African and Asian leopards are highly differentiated at the genomic level
Johanna L. A. Paijmans,Johanna L. A. Paijmans,Johanna L. A. Paijmans,Axel Barlow,Axel Barlow,Matthew S. Becker,James A. Cahill,James A. Cahill,Joerns Fickel,Joerns Fickel,Daniel W. Förster,Katrin Gries,Stefanie Hartmann,Rasmus Worsøe Havmøller,Kirstin Henneberger,Christian Kern,Andrew C. Kitchener,Andrew C. Kitchener,Eline D. Lorenzen,Frieder Mayer,Stephen J. O'Brien,Stephen J. O'Brien,Johanna von Seth,Johanna von Seth,Mikkel-Holder S. Sinding,Göran Spong,Olga Uphyrkina,Bettina Wachter,Michael V. Westbury,Michael V. Westbury,Love Dalén,Love Dalén,Jong Bhak,Jong Bhak,Andrea Manica,Michael Hofreiter +35 more
TL;DR: This paper found that Asian leopards are broadly monophyletic with respect to African leopard across almost their entire nuclear genomes, and that the deep divergence between the African subspecies and Asian populations contrasts with the much shallower divergence among putative Asian subspecies.
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Transient Linkage Disequilibrium in Drosophila
TL;DR: A transient linkage disequilibria is described between two allozyme loci in a laboratory population of Drosophila melanogaster to estimate genetic variation within natural populations.
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Genomic evidence for the Chinese mountain cat as a wildcat conspecific (Felis silvestris bieti) and its introgression to domestic cats.
He Yu,Yue-Ting Xing,Hao Meng,Bing He,Wen-Jing Li,Xin-Zhang Qi,Jian-You Zhao,Yan Zhuang,Xiao Xu,Nobuyuki Yamaguchi,Carlos A. Driscoll,Stephen J. O'Brien,Stephen J. O'Brien,Shu-Jin Luo,Shu-Jin Luo +14 more
TL;DR: The Qinghai-Tibet Plateau endemic Chinese mountain cat has a controversial taxonomic status, whether it is a true species or a wildcat (Felis silvestris) subspecies and whether it has contributed to cat (F. s. catus) domestication in East Asia as discussed by the authors.