S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
Papers
More filters
Journal Article
Quantitative Polymerase Chain Reaction-based Assay for Estimating DNA Yield Extracted from Domestic Cat Specimens
TL;DR: A quantitative polymerase chain reaction (PCR) assay has been developed for the quantification of genomic DNA extracted from domestic cat samples, which targets highly repetitive genomic short interspersed nuclear elements (SINE).
Journal ArticleDOI
Serum Antibody to Rift Valley Fever Virus in African Carnivores
TL;DR: The results of an extensive RVF serological survey among a diversity of African carnivore species show that cattle, sheep, goats, dogs, cats, mice, hamsters, rats, camels, water buffaloes, horses, monkeys, and humans are known to be susceptible to RVFV.
Journal ArticleDOI
Hypervariable genomic variation to reconstruct the natural history of populations: Lessons from the big cats
TL;DR: The interpretation of the extent of genetic diversity for minisatellite DNA in the cheetah is reviewed and the potential application of a second class of hypervariable DNA, microsatellite DNA, as a molecular tool to examine the natural histories of felid populations is considered.
Journal ArticleDOI
Mapping of the Domestic Cat “SILVER” Coat Color Locus Identifies a Unique Genomic Location for Silver in Mammals
Marilyn Menotti-Raymond,Victor A. David,Eduardo Eizirik,Melody E. Roelke,Helya Ghaffari,Stephen J. O'Brien +5 more
TL;DR: The mapping of a novel locus for SILVER offers much promise in identifying a gene that may help elucidate aspects of pheomelanogenesis, a pathway that has been very elusive, and illustrates the promise of the cat genome project in increasing the understanding of basic biological processes of general relevance for mammals.
Journal ArticleDOI
Molecular Analysis of the Human Serum Amyloid A (SAA) Gene Family
TL;DR: The study of SAA probe hybridization patterns in human DNA cleaved with restriction endonucleases found invariant patterns except for a two‐allele restriction fragment length polymorphism (RFLP) with Hind III, showing that the SAA gene family comprises at least three members in the haploid human genome.