S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Chromosomal mapping of lysosomal enzyme structural genes in the domestic cat.
TL;DR: A panel of 42 rodent x cat somatic cell hybrids has been used to assign seven structural genes for lysosomal enzymes to specific chromosomes in the domestic cat, expanding the genetic map of the cat and reaffirm the extensive syntenic homology between the chromosome maps of man and cat.
Book ChapterDOI
Molecular genetic characterization of two insular Asian cat species, Bornean bay cat and Iriomote cat
Warren E. Johnson,Fumiharu Shinyashiki,Marilyn Menotti Raymond,Carlos A. Driscoll,Charles Leh,Mel Sunquist,L. A. Johnston,M. Bush,David E. Wildt,Naoya Yuhki,Stephen J. O'Brien +10 more
TL;DR: The contrasting patterns of the genetic variation of Bornean bay cat and Iriomote cat likely reflect different natural histories for these two island cat taxa.
Journal ArticleDOI
Bvr-1, a restriction locus of a type C RNA virus in the feline cellular genome: identification, location, and phenotypic characterization in cat X mouse somatic cell hybrids
TL;DR: Reverse selection experiments on 6-thioguanine demonstrated that a restriction gene, tentatively named Bvr-1, was linked to the feline structural genes for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase in cats, probably on the X-chromosome.
Journal ArticleDOI
Allergy/hypersensitivity reactions as a predisposing factor to complex regional pain syndrome I in orthopedic patients.
TL;DR: A positive history for allergy/hypersensitivity reactions is a predisposing condition for CRPS I in this subset of orthopedic patients and these hypersensitivity reactions may prove important in gaining a better understanding in the pathophysiology ofCRPS I as a regional pain syndrome.
Journal ArticleDOI
Analysis of BCR-ABL1 tyrosine kinase domain mutational spectra in primitive chronic myeloid leukemia cells suggests a unique mutator phenotype.
H Grant,Xiaoyan Jiang,Justin Stebbing,Letizia Foroni,Charles Craddock,Michael J. Griffiths,Richard E. Clark,Stephen J. O'Brien,Jamshid S. Khorashad,Gareth Gerrard,Lihui Wang,Julie Irving,M Wang,L Karran,Martin J. S. Dyer,Donna L. Forrest,K Page,Connie J. Eaves,Adrian Woolfson +18 more
TL;DR: Analysis of BCR–ABL1 tyrosine kinase domain mutational spectra in primitive chronic myeloid leukemia cells suggests a unique mutator phenotype.