S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
Papers
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Journal ArticleDOI
CRISPR-mediated gene editing for the surgeon scientist.
TL;DR: Gene editing is likely to play an important role in future research in many aspects of the surgery arena as well as with other gene-editing systems and future applications, with a focus on applications of relevance to the surgeon scientist.
Patent
Stromal cell derived factor-1 (sdf-1) and method of use for diagnostic and prognostic indicator of aids pathogenesis
TL;DR: A nucleic acid sequence having a single nucleotide mutation in the 3' untranslated region of the mRNA transcript of the structural gene for stromal derived factor (SDF1-3'A) is provided in this paper.
Journal ArticleDOI
Abstracts of meeting presentations (Part 10 of 11)
L.A. Menlove,Elizabeth B. Robson,L.U. Lamm,John L. Hamerton,Susan Povey,N.E. Morton,Dirk Bootsma,Kenneth K. Kidd,Thomas B. Shows,Phyllis J. McAlpine,R.L. Miller,C.W. Partridge,Frank H. Ruddle,P.S. Gerald,Karl-Heinz Grzeschik,Malcolm A. Ferguson-Smith,David Cox,Andries Westerveld,S. Naylor,O.J. Miller,D. Drayna,P.N. Goodfellow,Victor A. McKusick,P. M. Conneally,A. de la Chapelle,Roland Berger,Thomas H. Roderick,P.A. Lalley,Muriel T. Davisson,Stephen J. O'Brien,James E. Womack,N. Créau-Goldberg,G. Echard,K.L. Moore,P. Meera Khan,Moyra Smith,Mark H. Skolnick,H.F. Willard +37 more
Journal ArticleDOI
Turf Toe: Diagnosis and Treatment.
TL;DR: The authors review the pertinent anatomy, mechanisms of injury, differential diagnosis, and possible long-term sequelae of turf toe, and present guidelines for treatment, return to activity, and prevention.
Journal ArticleDOI
New Gene Variants Associated with the Risk of Chronic HBV Infection
Mengjie Fan,Jing Wang,Sa Wang,Tengyan Li,Hong Pan,Hankui Liu,Huifang Xu,Daria V. Zhernakova,Stephen J. O'Brien,Stephen J. O'Brien,Zhenru Feng,Le Chang,Erhei Dai,Jianhua Lu,Hong-Li Xi,Yanyan Yu,Jianguo Zhang,Binbin Wang,Zheng Zeng +18 more
TL;DR: A two stage genome wide association study in a cohort of Chinese patients designed to discover single nucleotide variants that associate with HBV infection and clearance of HBV found two significant gene associations that suggest the influence of DOCK8 and CA9 as potential risk genetic factors in the persistence ofHBV infection.