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Stephen J. O'Brien

Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics

Publications -  1074
Citations -  98793

Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.

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Chromosomal localization of the genes encoding two forms of the G protein β polypeptide, β1 and β3, in man

TL;DR: The present studies were designed to determine whether the gene encoding beta 3 is linked to either the beta 1 or the beta 2 gene, and indicate that there is considerable diversity in the genomic organization of the beta subunit family.
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Risk Factors for Early Failure after Thermal Capsulorrhaphy

TL;DR: Thermal capsular shrinkage may be of limited value for patients who have had prior operations or have a history of multiple dislocations, and should be used cautiously in patients with multidirectional instability or in those who are involved in contact sports.
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The Pattern of Phylogenomic Evolution of the Canidae

TL;DR: Zoo-FISH probes from flow-sorted chromosomes of the Japanese raccoon dog are used to examine two phylogenetically divergent canids, indicating an ancestral episode of extensive centric fission leading to an ancestral canid genome organization that was subsequently reorganized by multiple chromosome fusion events in some but not all Canidae lineages.
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Segmental aneuploidy as a probe for structural genes in Drosophila: mitochondrial membrane enzymes.

TL;DR: A method for detecting possible structural genes in D. melanogaster based on gene dosage dependency is presented, and by making thirty crosses between Y-autosome translocations, and an attached-4 cross, it is possible to produce large duplications for every autosomal region with the exception of 83DE.
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A 1.5-Mb-resolution radiation hybrid map of the cat genome and comparative analysis with the canine and human genomes.

TL;DR: The improved RH comparative map provides a useful tool to facilitate positional cloning studies in the feline model and refined the pseudoautosomal region and boundary in the cat and show that it is markedly longer than those of human or mouse.