S
Stephen J. O'Brien
Researcher at Saint Petersburg State University of Information Technologies, Mechanics and Optics
Publications - 1074
Citations - 98793
Stephen J. O'Brien is an academic researcher from Saint Petersburg State University of Information Technologies, Mechanics and Optics. The author has contributed to research in topics: Population & Gene. The author has an hindex of 153, co-authored 1062 publications receiving 93025 citations. Previous affiliations of Stephen J. O'Brien include University College Cork & QIMR Berghofer Medical Research Institute.
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Journal ArticleDOI
Mapping of an endogenous retroviral sequence to human chromosome 18.
TL;DR: Isolation of the homologous locus from chimpanzee DNA indicated that the integration event preceded the evolutionary divergence of chimpanzees and man.
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Genetic characterization of feline leukemia virus from Florida panthers.
Meredith A. Brown,Mark W. Cunningham,Alfred L. Roca,Jennifer L. Troyer,Jennifer L. Troyer,Warren E. Johnson,Stephen J. O'Brien +6 more
TL;DR: The emergent strain of FeLV, a novel subgroup A, was probably transmitted to panthers by a domestic cat.
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Population Characteristics of DNA Fingerprints in Humpback Whales (Megaptera novaeangliae)
C. S. Baker,Dennis A. Gilbert,Mason T. Weinrich,R. H. Lambertsen,John Calambokidis,B. McArdle,G. K. Chambers,Stephen J. O'Brien +7 more
TL;DR: The relationship between DNA fingerprint similarities and geographic distance suggests that nuclear gene flow between regional subpopulations within the North Pacific is restricted by relatively low rates of migratory interchange between breeding grounds or assortative mating on common wintering grounds.
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Contrasting origin of B chromosomes in two cervids (Siberian roe deer and grey brocket deer) unravelled by chromosome-specific DNA sequencing.
Alexey I. Makunin,I. G. Kichigin,Denis M. Larkin,Patricia C. M. O’Brien,Malcolm A. Ferguson-Smith,Fengtang Yang,Anastasiya A. Proskuryakova,N.V. Vorobieva,Ekaterina Chernyaeva,Stephen J. O'Brien,Alexander S. Graphodatsky,Vladimir A. Trifonov +11 more
TL;DR: It is hypothesized that the B chromosomes of these two cervid species represent different stages of B chromosome sequences evolution: probably nascent and similar to autosomal copies in brocket deer, highly derived in roe deer, and based on the presence of the same orthologous protooncogenes in canids and broaket deer Bs.
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Diversity and Duplication of DQB and DRB-Like Genes of the MHC in Baleen Whales (Suborder: Mysticeti)
TL;DR: Comparison of inferred protein sequence of the DRB3-like locus suggested convergence with the DQB, perhaps resulting from intergenic conversion or recombination, and both loci showed low diversity among species and apparent loss of function or altered function including interruption of reading frames.