S
Stephen M. Collins
Researcher at McMaster University
Publications - 343
Citations - 28290
Stephen M. Collins is an academic researcher from McMaster University. The author has contributed to research in topics: Irritable bowel syndrome & Colitis. The author has an hindex of 86, co-authored 320 publications receiving 25646 citations. Previous affiliations of Stephen M. Collins include Hamilton Health Sciences & National Institutes of Health.
Papers
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Journal ArticleDOI
The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice.
Premysl Bercik,Emmanuel Denou,Josh Collins,Wendy Jackson,Jun Lu,Jennifer Jury,Yikang Deng,Patricia Blennerhassett,Joseph Macri,Kathy D. McCoy,Elena F. Verdu,Stephen M. Collins +11 more
TL;DR: The intestinal microbiota influences brain chemistry and behavior independently of the autonomic nervous system, gastrointestinal-specific neurotransmitters, or inflammation.
Journal ArticleDOI
Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome.
Giovanni Barbara,Vincenzo Stanghellini,Roberto De Giorgio,Cesare Cremon,Graeme S. Cottrell,Donatella Santini,Gianandrea Pasquinelli,Antonio Maria Morselli-Labate,Eileen F. Grady,Nigel W. Bunnett,Stephen M. Collins,Roberto Corinaldesi +11 more
TL;DR: Only mast cells in close proximity to nerves were significantly correlated with severity and frequency of abdominal pain/discomfort, and mediator release in proximity to mucosal innervation may contribute to abdominal pain perception in IBS patients.
Journal ArticleDOI
The interplay between the intestinal microbiota and the brain
TL;DR: How this extended communication system might influence a broad spectrum of diseases, including irritable bowel syndrome, psychiatric disorders and demyelinating conditions such as multiple sclerosis is reviewed.
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The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut–brain communication
Premysl Bercik,Amber J. Park,David A. Sinclair,A. Khoshdel,Jun Lu,Xianxi Huang,Yikang Deng,Patricia Blennerhassett,Margaret Fahnestock,Deborah Moine,Bernard Berger,Jan D. Huizinga,Wolfgang Kunze,Peter G. McLean,Gabriela Bergonzelli,Stephen M. Collins,Elena F. Verdu +16 more
TL;DR: The probiotic Bifidobacterium longum NCC3001 normalizes anxiety‐like behavior and hippocampal brain derived neurotrophic factor (BDNF) in mice with infectious colitis and test whether the anxiolytic effect of B. longum involves vagal integrity, and changes in neural cell function.
Journal ArticleDOI
The role of psychological and biological factors in postinfective gut dysfunction
K.A Gwee,Y. L. Leong,C. Graham,McKendrick Mw,Stephen M. Collins,Stephen J Walters,JE Underwood,Read Nw +7 more
TL;DR: Psychological factors most clearly predict the development of IBS symptoms after gastroenteritis but biological mechanisms also contribute towards the expression of symptoms.