S
Stephen R. Wisniewski
Researcher at University of Pittsburgh
Publications - 432
Citations - 46155
Stephen R. Wisniewski is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Major depressive disorder & Traumatic brain injury. The author has an hindex of 100, co-authored 401 publications receiving 41503 citations.
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Journal ArticleDOI
Acute and Longer- Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report
A. John Rush,Madhukar H. Trivedi,Stephen R. Wisniewski,Andrew A. Nierenberg,Jonathan W. Stewart,Diane Warden,George Niederehe,Michael E. Thase,Philip W. Lavori,Barry D. Lebowitz,Patrick J. McGrath,Jerrold F. Rosenbaum,Harold A. Sackeim,David J. Kupfer,James F. Luther,Maurizio Fava +15 more
TL;DR: The acute and longer-term treatment outcomes associated with each of four successive steps in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial are described and compared.
Journal ArticleDOI
Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice
Madhukar H. Trivedi,A. John Rush,Stephen R. Wisniewski,Andrew A. Nierenberg,Diane Warden,Louise Ritz,Grayson Norquist,Robert H Howland,Barry D. Lebowitz,Patrick J. McGrath,Kathy Shores-Wilson,Melanie M. Biggs,Goundappa K. Balasubramani,Maurizio Fava +13 more
TL;DR: The response and remission rates in this highly generalizable sample with substantial axis I and axis III comorbidity closely resemble those seen in 8-week efficacy trials.
Journal ArticleDOI
Treatment of Traumatic Brain Injury with Moderate Hypothermia
Donald W. Marion,Louis E. Penrod,Sheryl F. Kelsey,Walter Obrist,Patrick M. Kochanek,Alan M. Palmer,Stephen R. Wisniewski,Steven T. DeKosky +7 more
TL;DR: A randomized, controlled trial compared the effects of moderate hypothermia and normothermia in 82 patients with severe closed head injuries and found thatHypothermia may limit some of the deleterious metabolic responses of traumatic brain injury.
Journal ArticleDOI
Sequenced treatment alternatives to relieve depression (STAR * D): rationale and design
A. John Rush,Maurizio Fava,Stephen R. Wisniewski,Philip W. Lavori,Madhukar H. Trivedi,Harold A. Sackeim,Michael E. Thase,Andrew A. Nierenberg,Frederic M. Quitkin,T. Michael Kashner,David J. Kupfer,Jerrold F. Rosenbaum,Jonathan E. Alpert,Jonathan W. Stewart,Patrick J. McGrath,Melanie M. Biggs,Kathy Shores-Wilson,Barry D. Lebowitz,Louise Ritz,George Niederehe +19 more
TL;DR: STAR*D as discussed by the authors is a multisite, prospective, randomized, multistep clinical trial of outpatients with nonpsychotic major depressive disorder, which compared various treatment options for those who do not attain a satisfactory response with citalopram, a selective serotonin reuptake inhibitor antidepressant.
Journal ArticleDOI
Medication Augmentation after the Failure of Ssris for Depression
Madhukar H. Trivedi,Maurizio Fava,Stephen R. Wisniewski,Michael E. Thase,Frederick M. Quitkin,Diane Warden,Louise Ritz,Andrew A. Nierenberg,Barry D. Lebowitz,Melanie M. Biggs,James F. Luther,Kathy Shores-Wilson,A. John Rush +12 more
TL;DR: Augmentation of citalopram with either sustained-release bupropion or buspirone appears to be useful in actual clinical settings, including a greater reduction in the number and severity of symptoms and fewer side effects and adverse events.