Stephen W. Coons

TL;DR: In a cohort of patients with grade 2 glioma who were younger than 40 years of age and had undergone subtotal tumor resection or who were 40 yearsof age or older, progression-free survival and overall survival were longer among those who received combination chemotherapy in addition to radiation therapy than amongThose who received radiation therapy alone.

TL;DR: It is concluded that temporally, proliferation and migration are mutually exclusive behaviors and cell density or non‐permissive substrates that inhibit cell motility favor a more proliferative phenotype.

TL;DR: Image-guided neuronavigation during surgical resection of MR imaging lesions to correlate directly specimen histopathology with localized dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging measurements and to establish accurate rCBV threshold values, which differentiate PTRE from tumor recurrence are established.

TL;DR: In this paper, gene expression profiles of human glioblastoma multiforme (GBM) cells were assessed from laser capture-microdissected GBM cells collected from paired patient tumor cores and white matter-invading cell populations.

TL;DR: PFS but not OS was improved for adult patients with LGG receiving RT + PCV versus RT alone, suggesting a delayed benefit for chemotherapy.