S
Steven G. Reed
Researcher at Infectious Disease Research Institute
Publications - 436
Citations - 29185
Steven G. Reed is an academic researcher from Infectious Disease Research Institute. The author has contributed to research in topics: Antigen & Adjuvant. The author has an hindex of 87, co-authored 421 publications receiving 26962 citations. Previous affiliations of Steven G. Reed include University of Washington & Corixa Corporation.
Papers
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Journal ArticleDOI
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major.
Patricia A. Darrah,Dipti T. Patel,Paula M De Luca,Ross W. B. Lindsay,Dylan F. Davey,Barbara J. Flynn,Søren T. Hoff,Peter Andersen,Steven G. Reed,Sheldon L. Morris,Mario Roederer,Robert A. Seder +11 more
TL;DR: The quality of a CD4+ T-cell cytokine response can be a crucial determinant in whether a vaccine is protective, and may provide a new and useful prospective immune correlate of protection for vaccines based on T-helper type 1 (TH1) cells.
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Key roles of adjuvants in modern vaccines
TL;DR: The potential benefits and importance of formulation and mechanisms of action of adjuvants are outlined and safety considerations are emphasized in the clinical development of effective adjuvant that will help facilitate effective next-generation vaccines against devastating infectious diseases.
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New horizons in adjuvants for vaccine development
TL;DR: The current state of adjuvant research and development and how formulation parameters can influence the effectiveness of adjuvants are outlined.
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New Perspectives on a Subclinical Form of Visceral Leishmaniasis
Roberto Badaró,T. C. Jones,Edgar M. Carvalho,Diana P. Sampaio,Steven G. Reed,Aldina Barral,R. Teixeira,Warren D. Johnson +7 more
TL;DR: During an epidemiological study of visceral leishmaniasis in an endemic region of Brazil, new perspectives emerged on a subclinical form of the disease, where a group of 86 children with antibody to Leishmania were identified.
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Interleukin 10 production correlates with pathology in human Leishmania donovani infections.
H.W. Ghalib,Marcia Regina Piuvezam,Yasir A. W. Skeiky,M. Siddig,F.A. Hashim,Ahmed M. Elhassan,D M Russo,Steven G. Reed +7 more
TL;DR: Results indicate the production of IL-10 during L. donovani infection, and suggest a role for this cytokine in the regulation of immune responsiveness during visceral leishmaniasis.