S
Suash Sharma
Researcher at Georgia Regents University
Publications - 51
Citations - 1892
Suash Sharma is an academic researcher from Georgia Regents University. The author has contributed to research in topics: Differential diagnosis & Cancer. The author has an hindex of 17, co-authored 49 publications receiving 1631 citations. Previous affiliations of Suash Sharma include All India Institute of Medical Sciences.
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Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis
TL;DR: The objective of this review is to critically evaluate the major mechanisms underlying stroke pathophysiology, with emphasis on potential novel targets for designing newer therapeutic modalities.
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Morphology of angiogenesis in human cancer: a conceptual overview, histoprognostic perspective and significance of neoangiogenesis.
TL;DR: A judicious combination of quantitative and qualitative microscopic angiogenic parameters, with emphasis on neoangiogenesis and vascular patterns wherever applicable, should be an integral component of a more consistent tumour staging system for accurate prognostic evaluation of tumours, selection of optimal anti‐angiogenic therapy and pertinent research.
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DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis
Rajneesh Pathania,Sabarish Ramachandran,Selvakumar Elangovan,Ravi Padia,Pengyi Yang,Senthilkumar Cinghu,Rajalakshmi Veeranan-Karmegam,Pachiappan Arjunan,Jaya P. Gnana-Prakasam,Fulzele Sadanand,Lirong Pei,Chang Sheng Chang,Jeong Hyeon Choi,Huidong Shi,Santhakumar Manicassamy,Puttur D. Prasad,Suash Sharma,Vadivel Ganapathy,Raja Jothi,Muthusamy Thangaraju +19 more
TL;DR: An essential role for DNMT1 is uncovered in MaSC and CSC maintenance and theDNMT1-ISL1 axis is identified as a potential therapeutic target for breast cancer treatment.
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Neurocytoma: a comprehensive review.
TL;DR: E Epidemiology, histogenesis, clinical profile, histology, neuroimaging and therapeutic modalities of neurocytomas have been comprehensively reviewed, with special emphasis on CN and extraventricular neurocyTomas and their atypical counterparts.
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Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth
Rajneesh Pathania,Sabarish Ramachandran,G. Mariappan,Priyanka Thakur,Huidong Shi,Jeong Hyeon Choi,Santhakumar Manicassamy,Ravindra Kolhe,Puttur D. Prasad,Suash Sharma,Bal L. Lokeshwar,Vadivel Ganapathy,Muthusamy Thangaraju +12 more
TL;DR: It is suggested that breast CSCs are intrinsically sensitive to genetic and epigenetic modifications and can therefore be significantly affected by epigenetic-based therapies, warranting further investigation of combined DNMT and HDAC inhibition in refractory or drug-resistant breast cancer.