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Subramanian Jambu

Other affiliations: National Chemical Laboratory
Bio: Subramanian Jambu is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topics: Catalysis & Allylic rearrangement. The author has an hindex of 6, co-authored 7 publications receiving 120 citations. Previous affiliations of Subramanian Jambu include National Chemical Laboratory.

Papers
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Journal ArticleDOI
TL;DR: A versatile and site-selective rhodium(III)-catalyzed aerobic oxidative alkenylation of arylacetamides including primary, secondary, and tertiary amides having a weak O-coordinating acetamide directing group with alkenes is described.

62 citations

Journal ArticleDOI
TL;DR: The detailed mechanistic investigation and DFT studies including the transition-state analysis support the postulate that the C-H allylation takes place at the ortho position of aromatic acids with allylic acetates followed by intramolecular cyclization at the allylic C(sp3)-H via a π-allylruthenium intermediate.

34 citations

Journal ArticleDOI
TL;DR: In these reactions, ortho-alkenylated aromatic/vinylic acids were prepared in good to excellent yields and a possible reaction mechanism involving ortho C-H activation and a five-membered r Rhodacycle formation was proposed and supported by the deuterium-labeling studies and isolation of a key rhodacycle intermediate.

28 citations

Journal ArticleDOI
TL;DR: The C-H alkylation of arylacetamides with activated alkenes such as substituted acrylates and vinyl sulphone in the presence of a ruthenium catalyst and organic acid via the weak O-coordination under the redox free version is described.
Abstract: The C–H alkylation of arylacetamides with activated alkenes such as substituted acrylates and vinyl sulphone in the presence of a ruthenium catalyst and organic acid via the weak O-coordination und...

21 citations

Journal ArticleDOI
TL;DR: An efficient Rh(III)-catalyzed redox-neutral weak O-coordinating vinylation and allylation of arylacetamides with allylic acetates with possible reaction mechanism involving π-allyl rhodium intermediate was suggested and further confirmed through deuterium labeling studies.

15 citations


Cited by
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Journal ArticleDOI
TL;DR: The mechanisms of Ru-catalyzed arylation, alkylation, and alkenylation of arenes are summarized, and these transformations can be categorized into cross-coupling with electrophiles or oxidative coupling with nucleophiles.
Abstract: Ru-Catalyzed aromatic C–H bond activation and functionalization have emerged as important topics because they have resulted in remarkable progress in organic synthesis Both experimental and theoretical studies of their mechanisms are important for the design of new synthetic methodologies In this review, a mechanistic view of the Ru-mediated C–H bond cleavage step is first given to reveal the C–H bond activation modes, including oxidative addition, metathesis and base-assisted deprotonation In this process, directing groups play an important role in determining the reactivity of the C–H bond The C–H bond activation generally leads to the formation of a Ru–C bond, which is further functionalized in the subsequent steps The mechanisms of Ru-catalyzed arylation, alkylation, and alkenylation of arenes are summarized, and these transformations can be categorized into cross-coupling with electrophiles or oxidative coupling with nucleophiles In addition, the mechanism of ortho-ruthenation-enabled remote C–H bond functionalization is also discussed

182 citations

Journal ArticleDOI
TL;DR: This review has summarized the recent progress in the oxidative olefination of sp2 and sp3 C–H bonds with special emphasis on distal, atroposelective, non-directed sp 2 and directed sp3 c–H oleFination.
Abstract: Transition metal-catalysed functionalizations of inert C–H bonds to construct C–C bonds represent an ideal route in the synthesis of valuable organic molecules. Fine tuning of directing groups, catalysts and ligands has played a crucial role in selective C–H bond (sp2 or sp3) activation. Recent developments in these areas have assured a high level of regioselectivity in C–H olefination reactions. In this review, we have summarized the recent progress in the oxidative olefination of sp2 and sp3 C–H bonds with special emphasis on distal, atroposelective, non-directed sp2 and directed sp3 C–H olefination. The scope, limitation, and mechanism of various transition metal-catalysed olefination reactions have been described briefly.

109 citations

Journal ArticleDOI
Chenhao Guo1, Bin Li1, Huilai Liu1, Xiaopeng Zhang1, Xinying Zhang1, Xuesen Fan1 
TL;DR: Interestingly, the selectivity to form the fused or spiro compounds could be switched by resorting to different additives, and the notable features of this protocol include simple substrates and excellent atom economy and regioselectivity.

88 citations

Journal ArticleDOI
11 Mar 2021-Chem
TL;DR: This review aims to embrace all the aspects of transition-metal-promoted C–H allylation reactions and shows that they trigger the allylic selectivity of an unsaturated hydrocarbon under proper metal-ligand combination.

79 citations