Sung Kwan Yoon

Bio: Sung Kwan Yoon is an academic researcher from Chosun University. The author has contributed to research in topics: Abdominal distension & Metabolic alkalosis. The author has an hindex of 2, co-authored 2 publications receiving 8 citations.

Clinical Approach in the Diagnosis of Acute Appendicitis

Abstract: Abdominal pain is the most common reason for consultation in the emergency department, and most of the times, its cause is an episode of acute appendicitis. However, the misdiagnosis rate of acute appendicitis is high due to the unusual presentation of the symptoms. Therefore, the clinician has to be very alert in order to establish a correct diagnosis.

Relationship Between Bird Diversity and Habitat along a Pine- Oak Successional Forest in Southern Mexico

Abstract: Few studies have related bird species richness and abundance with vegetation structure at different successional stages in pine-oak forests of Mexico. We studied changes in the bird community across three successional stages of pine-oak forest: early, intermediate, and mature. Also, we related bird community attributes—including generalist and specialist birds—with vegetation variables. We analyzed the vegetation and estimated bird abundances in 10-min-count periods in 10 circular plots per successional stage. We recorded a total of 71 bird species: 21 were specialists and 50 were generalists. The completeness of species richness was between 79 and 88% in the sampled habitats. Diversity profiles were consistently larger in the intermediate stage, except for its species richness that was not different between this and the early stage. We found a more richness and a higher number of individuals of generalist in the early and intermediate stages. The abundance of specialists was higher in the mature forest. An ordination analysis showed that generalists were associated to different variables. This suggests that these species can adapt to different forest conditions. Some specialist birds were more abundant in sites with high dominance of trees. Our results confirm the importance of maintaining not only mature forests but also young successional stages in order to conserve the species typical of secondary pine-oak forest bird species.

Identification of SLC26A3 Mutations in a Korean Patient with Congenital Chloride Diarrhea

Abstract: Congenital chloride diarrhea (CLD) is an autosomal recessive disorder with the hallmark of persistent watery Cl--rich diarrhea from birth. Mutations in the solute carrier family 26, member 3 (SLC26A3) gene, which encodes a coupled Cl-/HCO3- exchanger in the ileum and colon, are known to cause CLD. Although there are a few reports of CLD patients in Korea, none of these had been confirmed by genetic analysis. Here, we describe the case of a Korean infant with clinical features of CLD. Using direct sequencing analysis, we identified 2 sequence variants: a missense variant of unknown significance (c.525G>C; p.Arg175 Ser) and a splicing mutation (c.2063-1G>T) in the SLC26A3 gene; these had been inherited from the father and mother, respectively. Whilst CLD is rare, its main symptom, diarrhea, is very common in infants. Hence, the diagnosis of CLD can prove difficult. Mutational analysis of the SLC26A3 gene should be considered as a viable method to confirm a diagnosis of CLD in Korean infants with persistent diarrhea.

Congenital chloride diarrhea in dizygotic twins.

Abstract: Congenital chloride diarrhea (CLD) is a rare inherited autosomal recessive disorder. Mutations of the solute carrier family 26 member 3 gene cause profuse, chloride ion rich diarrhea, which results in hypochloremia, hyponatremia and metabolic alkalosis with dehydration. If a fetal ultrasound shows bowel dilatation suggestive of bowel obstruction, or if a neonate shows persistent diarrhea and metabolic alkalosis, CLD should be considered in the differential diagnosis. The severity of CLD varies, but early detection and early therapy can prevent complications including growth failure. We report a case of dizygotic twins affected by CLD who had been born to non-consanguineous parents. Both of them showed growth failure, but one of the twins experienced worse clinical course. He showed developmental delay, along with dehydration and severe electrolyte imbalance. He was diagnosed with CLD first at 6-month age, and then the other one was also diagnosed with CLD.