S
Sunil Maharjan
Researcher at Public Health England
Publications - 10
Citations - 3372
Sunil Maharjan is an academic researcher from Public Health England. The author has contributed to research in topics: Klebsiella pneumoniae & New Delhi metallo-beta-lactamase 1. The author has an hindex of 8, co-authored 9 publications receiving 3104 citations. Previous affiliations of Sunil Maharjan include Health Protection Agency.
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Journal ArticleDOI
Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study
Karthikeyan Kumarasamy,Mark Toleman,Timothy R. Walsh,Jay Bagaria,Fafhana Butt,Ravikumar Balakrishnan,Uma Chaudhary,Michel Doumith,Christian G. Giske,Seema Irfan,Padma Krishnan,Anil Kumar,Sunil Maharjan,Shazad Mushtaq,Tabassum Noorie,David L. Paterson,A. Pearson,Claire Perry,Rachel Pike,Bhargavi Rao,Ujjwayini Ray,Jayanta B. Sarma,Madhu Sharma,Elizabeth Sheridan,M A Thirunarayan,Jane F. Turton,Supriya Upadhyay,Marina Warner,William Welfare,David M. Livermore,Neil Woodford +30 more
TL;DR: The prevalence of NDM-1, in multidrug-resistant Enterobacteriaceae in India, Pakistan, and the UK is investigated, and co-ordinated international surveillance is needed.
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Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates
David M. Livermore,Shazad Mushtaq,Marina Warner,Jiancheng Zhang,Sunil Maharjan,Michel Doumith,Neil Woodford +6 more
TL;DR: ACHn-490 has potent activity versus carbapenem-resistant isolates, except those also harbouring 16S rRNA methylases; isepamicin is also widely active, though less potent than ACHN-490.
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Activities of NXL104 Combinations with Ceftazidime and Aztreonam against Carbapenemase-Producing Enterobacteriaceae
David M. Livermore,Shazad Mushtaq,Marina Warner,Jiancheng Zhang,Sunil Maharjan,Michel Doumith,Neil Woodford +6 more
TL;DR: Combinations of NXL104 with ceftazidime and aztreonam were tested against carbapenem-resistant members of the Enterobacteriaceae and metallo-β-lactamases were resistant.
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False extended-spectrum β-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porins
Alejandro Beceiro,Sunil Maharjan,Tom Gaulton,Michel Doumith,Nelson C. Soares,Hiran Dhanji,Marina Warner,Maeve Doyle,M. L. Hickey,Gordon Downie,Germán Bou,David M. Livermore,Neil Woodford +12 more
TL;DR: 'cefpiromase' or 'cefepimase' ESBL phenotype of the clinical isolates non-susceptible to cefpirome and cefepime resulted from high expression of TEM-1 or OXA-1 β-lactamases combined with loss of porins.
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Early (2008-2010) hospital outbreak of Klebsiella pneumoniae producing OXA-48 carbapenemase in the UK
Claire P. Thomas,Luke S. P. Moore,Luke S. P. Moore,Nazik Elamin,Michel Doumith,Jiancheng Zhang,Sunil Maharjan,Marina Warner,Claire Perry,Jane F. Turton,Clare Johnstone,Annette Jepson,Neill Duncan,Alison Holmes,Alison Holmes,David M. Livermore,David M. Livermore,Neil Woodford +17 more
TL;DR: An early and prolonged outbreak in the UK of Klebsiella pneumoniae producing OXA-48 carbapenemase affecting a predominantly renal cohort in a West London hospital is reported.