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Surender Singh

Bio: Surender Singh is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Medicine & Arthritis. The author has an hindex of 31, co-authored 121 publications receiving 3150 citations. Previous affiliations of Surender Singh include Delhi Institute of Pharmaceutical Sciences and Research & Hamdard University.


Papers
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TL;DR: Oral administration of its aqueous-ethanolic (50%, v/v) extract led to significant blood glucose lowering effect in normal, glucose-fed hyperglycaemic and alloxan-induced diabetic rats.

188 citations

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TL;DR: OSSO appears to modulate both humoral and cell-mediated immune responsiveness and these immunomodulatory effects may be mediated by GABAergic pathways.

187 citations

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TL;DR: The hepatoprotective effect of aqueous-ethanolic extract of leaves of kasondi was studied on rat liver damage induced by paracetamol and ethyl alcohol by monitoring serum transaminase, alkaline posphatase, serum cholesterol, serum total lipids and histopathological alterations.

145 citations

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TL;DR: The fixed oil of Ocimum sanctum (Labiatae) was found to possess significant anti-inflammatory activity against carrageenan- and different other mediator-induced paw edema in rats, which support the dual inhibition of arachidonate metabolism.

145 citations

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TL;DR: Nineteen new 2-pyrazoline bearing benzenesulfonamide derivatives were synthesized by condensing chalcones with 4-hydrazinonbenzenes sulfuronamide hydrochloride by means of IR, NMR, mass spectroscopic and elemental analyses data, finding two compounds found to be more active than celecoxib throughout the study.

141 citations


Cited by
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TL;DR: The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors.
Abstract: The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors. While the organization of the book is similar to previous editions, major emphasis has been placed on disorders that affect multiple organ systems. Important advances in genetics, immunology, and oncology are emphasized. Many chapters of the book have been rewritten and describe major advances in internal medicine. Subjects that received only a paragraph or two of attention in previous editions are now covered in entire chapters. Among the chapters that have been extensively revised are the chapters on infections in the compromised host, on skin rashes in infections, on many of the viral infections, including cytomegalovirus and Epstein-Barr virus, on sexually transmitted diseases, on diabetes mellitus, on disorders of bone and mineral metabolism, and on lymphadenopathy and splenomegaly. The major revisions in these chapters and many

6,968 citations

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TL;DR: 45 plants and their products that have been mentioned/used in the Indian traditional system of medicine and have shown experimental or clinical anti-diabetic activity are reviewed.

1,641 citations

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TL;DR: Ginger is a strong anti-oxidant substance and may either mitigate or prevent generation of free radicals, and is considered a safe herbal medicine with only few and insignificant adverse/side effects.

1,300 citations

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TL;DR: Cinnamon, clove and lime oils were found to be inhibiting both gram-positive and gram-negative bacteria, whereas aniseed, eucalyptus and camphor oils were least active against the tested bacteria.
Abstract: To evaluate the antibacterial activity of 21 plant essential oils against six bacterial species. The selected essential oils were screened against four gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus vulgaris) and two gram-positive bacteria Bacillus subtilis and Staphylococcus aureus at four different concentrations (1:1, 1:5, 1:10 and 1:20) using disc diffusion method. The MIC of the active essential oils were tested using two fold agar dilution method at concentrations ranging from 0.2 to 25.6 mg/ml. Out of 21 essential oils tested, 19 oils showed antibacterial activity against one or more strains. Cinnamon, clove, geranium, lemon, lime, orange and rosemary oils exhibited significant inhibitory effect. Cinnamon oil showed promising inhibitory activity even at low concentration, whereas aniseed, eucalyptus and camphor oils were least active against the tested bacteria. In general, B. subtilis was the most susceptible. On the other hand, K. pneumoniae exhibited low degree of sensitivity. Majority of the oils showed antibacterial activity against the tested strains. However Cinnamon, clove and lime oils were found to be inhibiting both gram-positive and gram-negative bacteria. Cinnamon oil can be a good source of antibacterial agents.

954 citations

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TL;DR: 86 natural medicines with regards to their origin, anti-diabetic active principles and/or pharmacological test results, which are commonly used in the traditional Chinese medical system and have demonstrated experimental or/and clinical anti-Diabetic effectiveness are reviewed.

900 citations