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Susan E. Logue

Researcher at National University of Ireland, Galway

Publications -  42
Citations -  11004

Susan E. Logue is an academic researcher from National University of Ireland, Galway. The author has contributed to research in topics: Unfolded protein response & Apoptosis. The author has an hindex of 27, co-authored 40 publications receiving 9766 citations. Previous affiliations of Susan E. Logue include Belfast City Hospital & National University of Ireland.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mediators of endoplasmic reticulum stress-induced apoptosis.

TL;DR: The role of the molecules that are activated during the UPR is examined in order to identify the molecular switch from the adaptive phase to apoptosis and how the activation of these molecules leads to the commitment of death and the mechanisms that are responsible for the final demise of the cell.
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Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy.

TL;DR: The results suggest that Bnip3 contributes to I/R injury which triggers a protective stress response with upregulation of autophagy and removal of damaged mitochondria.
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Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

TL;DR: It is shown that IL-1α is a substrate for granzyme B and that proteolysis potently enhanced the biological activity of this cytokine in vitro as well as in vivo, and granzymes B-processed IL- 1α exhibited more potent activity as an immunoadjuvant in–vivo.
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New directions in ER stress-induced cell death

TL;DR: The role of ER localized proteins in sensing and triggering ER stress-induced death signals with particular emphasis on the contribution of calcium signaling and Bcl-2 family members to the execution phase of this process is highlighted.