S
Susan I. Ramos
Researcher at University of Virginia Health System
Publications - 9
Citations - 963
Susan I. Ramos is an academic researcher from University of Virginia Health System. The author has contributed to research in topics: Adenosine receptor & Reperfusion injury. The author has an hindex of 8, co-authored 9 publications receiving 910 citations.
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Journal ArticleDOI
Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells.
Avril V. Somlyo,Dawn Bradshaw,Susan I. Ramos,Cheryl Murphy,Charles E. Myers,Andrew P. Somlyo +5 more
TL;DR: The Rho-kinase inhibitor, Y-27632, inhibited in vitro chemotactic migration to bone marrow fibroblast conditioned media and metastatic growth in immune-compromised mice of highly invasive human prostatic cancer (PC3) cells, and it is concluded that invasiveness of human prostate cancer is facilitated by the Rho/Rho-Kinase pathway.
Journal ArticleDOI
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes.
Zequan Yang,Yuan-Ji Day,Marie-Claire Toufektsian,Yaqin Xu,Susan I. Ramos,Melissa A. Marshall,Brent A. French,Joel Linden +7 more
TL;DR: It is shown that CD4+ but not CD8+ T lymphocytes contribute to myocardial ischemia/reperfusion injury and is strongly suggested that the infarct-sparing effect of A2AR activation is primarily due to inhibition of CD4-cell accumulation and activation in the reperfused heart.
Journal ArticleDOI
Infarct-Sparing Effect of A2A-Adenosine Receptor Activation Is Due Primarily to Its Action on Lymphocytes
Zequan Yang,Yuan-Ji Day,Marie-Claire Toufektsian,Susan I. Ramos,Melissa A. Marshall,Xin-Qun Wang,Brent A. French,Joel Linden +7 more
TL;DR: The results indicate that A2AAR activation on bone marrow–derived cells, specifically T or B lymphocytes, is responsible for the infarct-sparing and antiinflammatory effects of ATL146e administered at the time of reperfusion after coronary occlusion.
Journal ArticleDOI
A2A Adenosine Receptors on Bone Marrow-Derived Cells Protect Liver from Ischemia-Reperfusion Injury
TL;DR: The data suggest that activation of the A2AR on bone marrow-derived cells is primarily responsible for protecting the liver from reperfusion injury.
Journal ArticleDOI
Are voltage-dependent ion channels involved in the endothelial cell control of vasomotor tone?
Xavier F. Figueroa,Chien-Chang Chen,Kevin P. Campbell,David N. Damon,Kathleen H. Day,Susan I. Ramos,Brian R. Duling +6 more
TL;DR: In the microcirculation, longitudinal conduction of vasomotor responses provides an essential means of coordinating flow distribution among vessels in a complex network.