S
Susannah J. Salter
Researcher at University of Cambridge
Publications - 27
Citations - 4025
Susannah J. Salter is an academic researcher from University of Cambridge. The author has contributed to research in topics: Gene & Population. The author has an hindex of 14, co-authored 24 publications receiving 3199 citations. Previous affiliations of Susannah J. Salter include Wellcome Trust & Wellcome Trust Sanger Institute.
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Journal ArticleDOI
Reagent and laboratory contamination can critically impact sequence-based microbiome analyses
Susannah J. Salter,Michael J. Cox,Elena M. Turek,Szymon T. Calus,William O.C.M. Cookson,Miriam F. Moffatt,Paul Turner,Paul Turner,Julian Parkhill,Nicholas J. Loman,Alan W. Walker,Alan W. Walker +11 more
TL;DR: It is demonstrated that contaminating DNA is ubiquitous in commonly used DNA extraction kits and other laboratory reagents, varies greatly in composition between different kits and kit batches, and that this contamination critically impacts results obtained from samples containing a low microbial biomass.
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Dense genomic sampling identifies highways of pneumococcal recombination
Claire Chewapreecha,Simon R. Harris,Nicholas J. Croucher,Claudia Turner,Claudia Turner,Claudia Turner,Pekka Marttinen,Lu Cheng,Alberto Pessia,David M. Aanensen,Alison E. Mather,Andrew J. Page,Susannah J. Salter,David Harris,François Nosten,François Nosten,David Goldblatt,Jukka Corander,Jukka Corander,Jukka Corander,Julian Parkhill,Paul Turner,Paul Turner,Paul Turner,Stephen D. Bentley,Stephen D. Bentley +25 more
TL;DR: In this article, the authors report whole-genome sequencing of 3,085 pneumococcal carriage isolates from a 2.4km(2) refugee camp, which provides unprecedented resolution of the process of recombination and its impact on population evolution.
Journal ArticleDOI
Recognizing the reagent microbiome.
Marcus C. de Goffau,Susanne Lager,Susannah J. Salter,Josef Wagner,Andreas Kronbichler,D. Stephen Charnock-Jones,Sharon J. Peacock,Sharon J. Peacock,Sharon J. Peacock,Gordon C. S. Smith,Julian Parkhill +10 more
TL;DR: Visual, statistical, methodical and ecological techniques are described to facilitate recognition of signals that represent contamination in the microbiome literature.
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Comprehensive Identification of Single Nucleotide Polymorphisms Associated with Beta-lactam Resistance within Pneumococcal Mosaic Genes
Claire Chewapreecha,Pekka Marttinen,Pekka Marttinen,Nicholas J. Croucher,Susannah J. Salter,Simon R. Harris,Alison E. Mather,William P. Hanage,David Goldblatt,François Nosten,Claudia Turner,Paul Turner,Stephen D. Bentley,Julian Parkhill +13 more
TL;DR: A genome-wide association study to identify single nucleotide polymorphisms (SNPs) and indels that could confer beta-lactam non-susceptibility using 3,085 Thai and 616 USA pneumococcal isolates as independent datasets for the variant discovery.
Journal ArticleDOI
Patent human infections with the whipworm, Trichuris trichiura, are not associated with alterations in the faecal microbiota.
Philip J. Cooper,Alan W. Walker,Jorge Reyes,Martha E. Chico,Susannah J. Salter,Maritza Vaca,Julian Parkhill +6 more
TL;DR: The data indicate that patent human infections with T. trichiura may have no effect on faecal microbiota but that A. lumbricoides colonisation might be associated with a disturbed microbiota.