S
Suzannah M. Schmidt-Malan
Researcher at Mayo Clinic
Publications - 35
Citations - 841
Suzannah M. Schmidt-Malan is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Staphylococcus epidermidis & Methicillin-resistant Staphylococcus aureus. The author has an hindex of 11, co-authored 32 publications receiving 363 citations.
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Journal ArticleDOI
Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections
Jessa Marie Makabenta,Ahmed Nabawy,Cheng-Hsuan Li,Suzannah M. Schmidt-Malan,Robin Patel,Vincent M. Rotello +5 more
TL;DR: The mechanisms by which nanomaterials can be used to target antibiotic-resistant bacterial infections are discussed, design elements and properties of nanomMaterials that can be engineered to enhance potency are highlighted, and recent progress and remaining challenges for clinical implementation are explored.
Journal ArticleDOI
Comparative activities of vancomycin, tigecycline and rifampin in a rat model of methicillin-resistant Staphylococcus aureus osteomyelitis
Paschalis Vergidis,Suzannah M. Schmidt-Malan,Jayawant N. Mandrekar,James M. Steckelberg,Robin Patel +4 more
TL;DR: Tigecycline plus rifampin resulted in a significant bacterial count decrease, an effect more prominent at 48 h than two weeks after treatment completion, and was not well tolerated at the dose studied.
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Exposure of Bacterial Biofilms to Electrical Current Leads to Cell Death Mediated in Part by Reactive Oxygen Species.
Cassandra L. Brinkman,Suzannah M. Schmidt-Malan,Melissa J. Karau,Kerryl E. Greenwood-Quaintance,Daniel J. Hassett,Jayawant N. Mandrekar,Robin Patel +6 more
TL;DR: The electricidal effect results in death of bacteria in biofilms, mediated, at least in part, by production of ROS.
Journal ArticleDOI
Antibiofilm Activity of Low-Amperage Continuous and Intermittent Direct Electrical Current.
Suzannah M. Schmidt-Malan,Melissa J. Karau,Julia Cede,Kerryl E. Greenwood-Quaintance,Cassandra L. Brinkman,Jayawant N. Mandrekar,Robin Patel +6 more
TL;DR: Low-amperage current or 4 h a day of intermittent current delivered using a variety of electrode compositions reduced P. aeruginosa, S. aureus, and S. epidermidis biofilms on a variety the surface materials and electrode compositions tested.
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In vitro activity of tedizolid against staphylococci isolated from prosthetic joint infections
TL;DR: The MIC and minimum biofilm bactericidal concentration (MBBC) of tedizolid and vancomycin against 97 isolates of Staphylococcus aureus and 74 isolates associated with prosthetic joint infection are determined.