S
Suzanne Hagan
Researcher at Glasgow Caledonian University
Publications - 38
Citations - 4315
Suzanne Hagan is an academic researcher from Glasgow Caledonian University. The author has contributed to research in topics: Kinase & Medicine. The author has an hindex of 18, co-authored 35 publications receiving 3812 citations. Previous affiliations of Suzanne Hagan include Vision-Sciences, Inc..
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Journal ArticleDOI
MAP kinase signalling pathways in cancer.
TL;DR: Recent findings and hypotheses on the role of MAPK pathways in cancer are discussed, with a focus on stress-activated pathways, which largely seem to counteract malignant transformation.
Journal ArticleDOI
Reduction of Raf-1 Kinase Inhibitor Protein Expression Correlates with Breast Cancer Metastasis
Suzanne Hagan,Fahd Al-Mulla,Elizabeth Mallon,Karin A. Oien,Rhona Ferrier,Barry A. Gusterson,Jorge J. Curto García,Walter Kolch +7 more
TL;DR: It is confirmed that in human breast cancer, RKIP is a metastasis suppressor gene whose expression must be down-regulated for metastases to develop, independent of other markers for breast cancer progression and prognosis.
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Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine.
TL;DR: An overview of the various putative tear fluid biomarkers that have been identified to date, ranging from ocular surface disease and retinopathies to cancer and multiple sclerosis, are shown.
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Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome.
Harriet C. T. Groom,Virginie C. Boucherit,Kerry Makinson,Edward Randal,Sarah Baptista,Suzanne Hagan,John W Gow,Frank M. Mattes,Judith Breuer,Jonathan R. Kerr,Jonathan P. Stoye,Kate N. Bishop +11 more
TL;DR: It is believed that the detection of neutralising activity that did not inhibit VSV-G pseudotyped MLV in at least four human serum samples indicates that XMRV infection may occur in the general population, although with currently uncertain outcomes.
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Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines.
TL;DR: The results suggest that loss of RKIP in malignant melanoma contributes to enhanced invasiveness of transformed cells and therefore to progression of the disease.