The ability to pattern functional polymers at different length scales is important for research fields including cell biology, tissue engineering and medicinal science and the development of optics and electronics. The interest and capabilities of polymer patterning have originated from the abundance of functionalities of polymers and a wide range of applications of the patterns. This paper reviews recent advances in top-down and bottom-up patterning of polymers using photolithography, printing techniques, self-assembly of block copolymers and instability-induced patterning. Finally, challenges and future directions are discussed from the point of view of both applicability and strategies for the surface patterning of polymers.

Patterning surfaces with functional polymers

We have reviewed the humidity sensors based on ceramic materials. We first discuss the operating principle of ceramic humidity sensors. This is followed by a section on the relationship between the conduction mechanism and microstructure characteristics of the sensing elements of ceramic humidity sensors. This part of the review is also focused on the methods for optimization of the microstructure of ceramic porous elements. The next section summarizes the information on the materials used for the ceramic humidity sensors fabrication and effect of dopants or hybrid compositions on the sensing ceramic-based materials. Then we analyze state-of-the-art techniques for producing ceramic sensors. The key research and technological challenges in the field are discussed at the end of the review. The review is based on 424 references published during from 1998–2013.

Recent trends of ceramic humidity sensors development: A review

Wearables as medical technologies are becoming an integral part of personal analytics, measuring physical status, recording physiological parameters, or informing schedule for medication. These continuously evolving technology platforms do not only promise to help people pursue a healthier life style, but also provide continuous medical data for actively tracking metabolic status, diagnosis, and treatment. Advances in the miniaturization of flexible electronics, electrochemical biosensors, microfluidics, and artificial intelligence algorithms have led to wearable devices that can generate real-time medical data within the Internet of things. These flexible devices can be configured to make conformal contact with epidermal, ocular, intracochlear, and dental interfaces to collect biochemical or electrophysiological signals. This article discusses consumer trends in wearable electronics, commercial and emerging devices, and fabrication methods. It also reviews real-time monitoring of vital signs using biosensors, stimuli-responsive materials for drug delivery, and closed-loop theranostic systems. It covers future challenges in augmented, virtual, and mixed reality, communication modes, energy management, displays, conformity, and data safety. The development of patient-oriented wearable technologies and their incorporation in randomized clinical trials will facilitate the design of safe and effective approaches.

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Wearables in Medicine

This review highlights recent developments in the synthesis of nanosized zeolites. The strategies available for their preparation (organic-template assisted, organic-template free, and alternative procedures) are discussed. Major breakthroughs achieved by the so-called zeolite crystal engineering and encompass items such as mastering and using the physicochemical properties of the precursor synthesis gel/suspension, optimizing the use of silicon and aluminium precursor sources, the rational use of organic templates and structure-directing inorganic cations, and careful adjustment of synthesis conditions (temperature, pressure, time, heating processes from conventional to microwave and sonication) are addressed. An on-going broad and deep fundamental understanding of the crystallization process, explaining the influence of all variables of this complex set of reactions, underpins an even more rational design of nanosized zeolites with exceptional properties. Finally, the advantages and limitations of these methods are addressed with particular attention to their industrial prospects and utilization in existing and advanced applications.

Advances in nanosized zeolites

This is the first comprehensive review on methods and materials for use in optical sensing of pH values and on applications of such sensors. The Review starts with an introduction that contains subsections on the definition of the pH value, a brief look back on optical methods for sensing of pH, on the effects of ionic strength on pH values and pKa values, on the selectivity, sensitivity, precision, dynamic ranges, and temperature dependence of such sensors. Commonly used optical sensing schemes are covered in a next main chapter, with subsections on methods based on absorptiometry, reflectometry, luminescence, refractive index, surface plasmon resonance, photonic crystals, turbidity, mechanical displacement, interferometry, and solvatochromism. This is followed by sections on absorptiometric and luminescent molecular probes for use pH in sensors. Further large sections cover polymeric hosts and supports, and methods for immobilization of indicator dyes. Further and more specific sections summarize the state of the art in materials with dual functionality (indicator and host), nanomaterials, sensors based on upconversion and 2-photon absorption, multiparameter sensors, imaging, and sensors for extreme pH values. A chapter on the many sensing formats has subsections on planar, fiber optic, evanescent wave, refractive index, surface plasmon resonance and holography based sensor designs, and on distributed sensing. Another section summarizes selected applications in areas, such as medicine, biology, oceanography, bioprocess monitoring, corrosion studies, on the use of pH sensors as transducers in biosensors and chemical sensors, and their integration into flow-injection analyzers, microfluidic devices, and lab-on-a-chip systems. An extra section is devoted to current challenges, with subsections on challenges of general nature and those of specific nature. A concluding section gives an outlook on potential future trends and perspectives.

Optical Sensing and Imaging of pH Values: Spectroscopies, Materials, and Applications

Recent research on an acrylamide-based photopolymerizable holographic recording material is presented. The recording characteristics of the material are discussed in detail in terms of sensitivity, diffraction efficiency, recording linearity, resolution limit, and sources of noise. Although the resolution is not sufficient for reflection holography, the recording characteristics are excellent for transmission gratings. The material was found to suffer no shrinkage during recording, and high-diffraction-efficiency slanted gratings were made. Finally, the suitability of this self-developing material to both double-exposure and real-time holographic interferometry is demonstrated.

Holographic recording characteristics of an acrylamide-based photopolymer.

Recent work on an acrylamide-based photopolymer holographic recording medium is presented The lifetime of recorded gratings is improved by the addition of cross-linking monomers Shelf life is also improved The effects of various constituents of the photosensitive material are studied to determine an optimum composition, and five xanthene dyes are compared as possible sensitizers for the system With the most sensitive dye and optimum concentrations of the other constituents an improved formulation is presented with high sensitivity and very high diffraction efficiency The new formulation also works well in reflection mode

Characterization of an acrylamide based dry photopolymer holographic recording material

A reflection hologram for visual indication of environmental humidity has been studied. The hologram is recorded in a self-developing photopolymer and changes color when exposed to a change in humidity and is fully reversible. The range of color change, reversibility, and the response time of the hologram have been studied in a controlled humidity environment. Fully reversible holograms with response times from few seconds to tens of minutes have been designed. Extremely sensitive bright visual humidity indicators, capable of dramatic color change within a few seconds of breathing on them are demonstrated.

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A visual indication of environmental humidity using a color changing hologram recorded in a self-developing photopolymer

Results from the investigation of the diffusion processes in a dry acrylamide-based photopolymer system are presented. The investigation is carried out in the context of experimental research on optimization of the high-spatial-frequency response of the photopolymer. Tracing the transmission holographic grating dynamics at short times of exposure is utilized to measure diffusion coefficients. The results reveal that two different diffusion processes contribute with opposite sign to the refractive-index modulation responsible for the diffraction grating buildup. Monomer diffusion from dark to bright fringe areas increases the refractive-index modulation. It is characterized with diffusion constant D0 = 1.6 × 10-7 cm2/s. A second diffusion process takes place during the recording. It decreases the refractive-index modulation and we ascribe it to diffusion of short-chain polymer molecules or radicals from bright to dark fringe areas. The estimated diffusion coefficient for this process is D0 = 6.35 × 10-10 cm2/s. The presence of the second process could be responsible for the poor high-spatial-frequency response of the investigated photopolymer system. Comparison with the diffusion in photopolymer systems known for their good response at high spatial frequencies shows that both investigated diffusion processes occur in a much faster time scale.

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Investigation of the diffusion processes in a self-processing acrylamide-based photopolymer system.

The humidity and temperature responses of a reflection hologram recorded in a self-processing photopolymer layer have been characterised by measurement of the position of the maximum intensity in the spectral response of the hologram. It has been demonstrated that such a hologram can be used for indication of the relative humidity (RH) in a specific temperature range. The operational range and reversibility of the holograms have been characterised in a controlled humidity and temperature environment. The humidity studies were carried out in the range from 10 to 80% RH and the temperature range under study was 15–50 °C.

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Suzanne Martin

Papers

Holographic recording characteristics of an acrylamide-based photopolymer.

Characterization of an acrylamide based dry photopolymer holographic recording material

A visual indication of environmental humidity using a color changing hologram recorded in a self-developing photopolymer

Investigation of the diffusion processes in a self-processing acrylamide-based photopolymer system.

Characterisation of the Humidity and Temperature Responses of a Reflection Hologram Recorded in Acrylamide-based Photopolymer