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Suzanne Oparil

Researcher at University of Alabama at Birmingham

Publications -  941
Citations -  122414

Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.

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Journal Article

Fixed combination of losartan and hydrochlorothiazide and reduction of risk of stroke.

TL;DR: The efficacy, tolerability, and convenience of losartan/HCTZ combination therapy may increase patient compliance and lower risk for stroke, a devastating outcome in patients with hypertension.
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Hypoxia-Induced Oxygen Tolerance: Maintenance of Endothelial Metabolic Function

TL;DR: In isolated perfused lungs 125I-MK351A binding reflects development of oxygen tolerance after hypoxia preadaptation and suggests that lung endothelial metabolic function is protected from oxygen toxicity.
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Altered responsiveness of regional brain dopamine and DOPAC levels to systemic administration of quinpirole, a dopamine D2 agonist, in DOCA/NaCl-hypertensive rats.

TL;DR: Quinpirole resulted in a significant increase in DA stores and decrease in DOPAC stores in most brain regions examined in both DOCA/NaCl-hypertensive rats and normotensive controls, presumably by inhibiting DA release through a presynaptic mechanism.
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Impact of olmesartan on blood pressure, endothelial function, and cardiovascular outcomes.

TL;DR: Large-scale, long-term studies are needed to confirm that olmesartan has vasoprotective effects that are independent of BP control and to determine whether these pleiotropic effects translate into improved CV disease outcomes.
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Efficacy of perindopril in the treatment of systemic hypertension

TL;DR: Perindopril increases arterial compliance and reverses left ventricular hypertrophy in hypertensive patients and is safe and well tolerated in patients with hypertension.