S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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ETA-receptor antagonist prevents and reverses chronic hypoxia-induced pulmonary hypertension in rat
TL;DR: Findings suggest that, in the lung, hypoxia induced an increase synthesis of endothelin-1, which acts locally on ETA receptors to cause pulmonary hypertension, right heart hypertrophy, and pulmonary vascular remodeling, while ETA-receptor blockade can both prevent and reverse these processes.
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Pathogenesis of Paroxysmal Hypertension Developing During and After Coronary Bypass Surgery: A Study of Hemodynamic and Humoral Factors
TL;DR: Evidence of enhanced sympathetic activity during surgery may be a useful predictor of the development of postoperative hypertension, particularly in patients with a longer history of angina of greater severity.
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Impact of renal denervation on 24-hour ambulatory blood pressure: results from SYMPLICITY HTN-3.
George L. Bakris,Raymond R. Townsend,Minglei Liu,Sidney Cohen,Ralph B. D'Agostino,John M. Flack,David E. Kandzari,Barry T. Katzen,Martin B. Leon,Laura Mauri,Manuela Negoita,William W. O'Neill,Suzanne Oparil,Krishna J. Rocha-Singh,Deepak L. Bhatt,Symplicity Htn Investigators +15 more
TL;DR: This trial did not demonstrate a benefit of renal artery denervation on reduction in ambulatory BP in either the 24-h or day and night periods compared with sham.
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Effects of Pressure Overload on Extracellular Matrix Expression in the Heart of the Atrial Natriuretic Peptide–Null Mouse
Dajun Wang,Suzanne Oparil,Ji An Feng,Peng Li,Gilbert J. Perry,Lan Bo Chen,Meiru Dai,Simon W.M. John,Yiu-Fai Chen +8 more
TL;DR: The hypothesis that atrial natriuretic peptide protects against pressure overload–induced cardiac hypertrophy and remodeling by negative modulation of genes involved in extracellular matrix deposition is supported.
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Refractory Hypertension Determination of Prevalence, Risk Factors, and Comorbidities in a Large, Population-Based Cohort
David A. Calhoun,John N. Booth,Suzanne Oparil,Marguerite R. Irvin,Daichi Shimbo,Daniel T. Lackland,George Howard,Monika M. Safford,Paul Muntner +8 more
TL;DR: The data indicate that although resistant hypertension is relatively common among treated patients with hypertension, true antihypertensive treatment failure is rare.