S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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Journal ArticleDOI
Kidney Disease, Hypertension Treatment, and Cerebral Perfusion and Structure.
Manjula Kurella Tamura,Sarah A. Gaussoin,Nicholas M. Pajewski,Greg Zaharchuk,Barry I. Freedman,Stephen R. Rapp,Alexander P. Auchus,William E. Haley,Suzanne Oparil,Jessica Kendrick,Christianne L. Roumie,Srinivasan Beddhu,Alfred K. Cheung,Jeff D. Williamson,John A. Detre,Sudipto Dolui,R. Nick Bryan,Ilya M. Nasrallah +17 more
TL;DR: In this article, the effects of hypertension treatment on cerebral perfusion and structure in those with and without CKD were studied in a randomized clinical trial, and the findings support the safety of intensive blood pressure treatment targets on brain health.
Journal ArticleDOI
The Health Outcomes Prevention and Evaluation 4 (HOPE 4) project: A successful community-based intervention to lower cardiovascular risk in people with hypertension.
TL;DR: The HOPE 4 project showed that a model of care led by non-physician health workers, supervised by primary care physicians, but also involving family members of the study participants and free medication, substantially improved cardiovascular risk and blood pressure control in the community.
Journal ArticleDOI
Ambulatory blood pressure results of symplicity HTN-3 trial
George L. Bakris,Raymond R. Townsend,John M. Flack,David E. Kandzari,William W. O'Neill,Ralph B. D'Agostino,Barry T. Katzen,Martin B. Leon,Minglei Liu,Laura Mauri,Manuela Negoita,Sidney Cohen,Suzanne Oparil,Krishna J. Rocha-Singh,Deepak L. Bhatt +14 more
Proceedings ArticleDOI
Op0208 effect of serum urate lowering with allopurinol on blood pressure in young adults
Angelo L. Gaffo,Angelo L. Gaffo,David A. Calhoun,Elizabeth J. Rahn,Suzanne Oparil,Paul Muntner,Li Peng,David T. Redden,Tanja Dudenbostel,Jeffrey Foster,Stephanie Biggers,Daniel I. Feig,Kenneth G. Saag +12 more
TL;DR: In the intention-to-treat analysis, urate -lowering therapy with allopurinol in young adults did not lead to reductions in blood pressure when compared with placebo, and there was a trend towards significant blood pressure decreases in the small participant subgroup with serum urate of > 6.5 mg/dL at baseline visit.
Journal ArticleDOI
366 ATRIAL NATRIURETIC PEPTIDE AND CYCLIC GUANOSINE MONOPHOSPHATE BLOCK THE STIMULATORY EFFECTS OF TRANSFORMING GROWTH FACTOR β1 ON EXTRACELLULAR MATRIX MESSENGER RIBONUCLEIC ACID EXPRESSION IN CULTURED PULMONARY ARTERY SMOOTH MUSCLE CELLS
TL;DR: It is suggested that atrial natriuretic peptide and its second messenger cGMP have antifibrogenic effect by blocking TGF-β1-induced ECM expression in PASMCs, which may play an important role in the pulmonary vascular remodeling.