S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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The orally active nonpeptide endothelin A-receptor antagonist A-127722 prevents and reverses hypoxia-induced pulmonary hypertension and pulmonary vascular remodeling in Sprague-Dawley rats.
Shi-Juan Chen,Yiu-Fai Chen,Terry J. Opgenorth,Jerry L. Wessale,Qing Cheng Meng,Joan Durand,Vick S. DiCarlo,Suzanne Oparil +7 more
TL;DR: The hypothesis that endogenous ET-1 plays a major role in hypoxic pulmonary vasoconstriction/hypertension, right heart hypertrophy, and pulmonary vascular remodeling is supported and it is suggested that ET-A receptor blockers may be useful in the treatment and prevention of hypoxia-induced pulmonary hypertension in humans.
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Apparent treatment resistant hypertension and risk for stroke, coronary heart disease and all-cause mortality
Marguerite R. Irvin,John N. Booth,Daichi Shimbo,Daniel T. Lackland,Suzanne Oparil,George Howard,Monika M. Safford,Paul Muntner,David A. Calhoun +8 more
TL;DR: Assessment of the association ofarent treatment-resistant hypertension with incident stroke, coronary heart disease, and all-cause mortality in Participants from the population-based REasons for Geographic And Racial Differences in Stroke (REGARDS) Study found aTRH was associated with an increased risk for coronaryHeart disease and all thecause mortality.
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Estrogen modulates TNF-α-induced inflammatory responses in rat aortic smooth muscle cells through estrogen receptor-β activation
Dongqi Xing,Wenguang Feng,Andrew P. Miller,Nathaniel M. Weathington,Yiu-Fai Chen,Lea Novak,J. Edwin Blalock,Suzanne Oparil +7 more
TL;DR: This data indicates that 17β-estradiol attenuates responses to endoluminal injury of the rat carotid artery, at least in part, by decreasing inflammatory mediator expression and neutrophi...
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Nutritional management of cardiovascular risk factors. A randomized clinical trial.
David A. McCarron,Suzanne Oparil,Alan Chait,R. Brian Haynes,Penny M. Kris-Etherton,Judith S. Stern,Lawrence M. Resnick,Sharon R. Clark,Cynthia D. Morris,Daniel C. Hatton,Jill A. Metz,Margaret McMahon,Scott Holcomb,Geoffrey W. Snyder,F. Xavier Pi-Sunyer +14 more
TL;DR: The Campbell's Center for Nutrition and Wellness plan is a comprehensive nutrition plan, convenient for both prescription and practice, and appears viable for effecting favorable dietary changes in patients at high risk for cardiovascular disease.
Journal ArticleDOI
Adherence and persistence with taking medication to control high blood pressure
Martha N. Hill,Nancy Houston Miller,Sabina DeGeest,Barry J. Materson,Henry R. Black,Joseph L. Izzo,Suzanne Oparil,Michael Weber +7 more
TL;DR: Improvements in adherence and persistence are likely to be achieved by supporting patient self-management, a team approach to patient care, technology-supported office practice systems, better methods to measure adherence, and less clinical inertia.