S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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Journal Article
Mechanism of the depressor action of LY171555, a selective dopamine D2 receptor agonist, in the anesthetized rat.
TL;DR: It is suggested that LY171555 decreases MAP and heart rate in anesthetized rats by inhibiting norepinephrine release from nerve endings through the peripheral dopamine D2 receptor and that the time course of the depressor response may be altered by LY 171555-induced AVP release, the magnitude of which appears to be dependent on the anesthetic agent.
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Circadian variations in blood pressure and their implications for the administration of antihypertensive drugs: is dosing in the evening better than in the morning?
Michel Burnier,Reinhold Kreutz,Krzysztof Narkiewicz,Sverre E. Kjeldsen,Suzanne Oparil,Giuseppe Mancia +5 more
TL;DR: The conclusion is that there is no convincing evidence that the administration of BP-lowering drugs in the evening provides any significant advantage in terms of quality of BP control, prevention of target organ damage or reduction of cardiovascular events.
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The role of the posterior hypothalamic area in the pathogenesis of hypertension in the spontaneously hypertensive rat
TL;DR: The increase in norepinephrine content in the absence of changes in turnover is interpreted to indicate increased noradrenergic input to the PHA of SHR and supports the hypothesis that noradRenergic pathways to thePHA are important in the development of hypertension in this model.
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Angiotensin extraction by trout tissues in vivo and metabolism by the perfused gill
TL;DR: During stress, elevated plasma catecholamines may reduce venous perfusion and thereby help maintain elevated circulating Angiotensin II levels through reduced venous metabolism.
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Metabolite ligands of estrogen receptor-β reduce primate coronary hyperreactivity
Rajesh G. Mishra,Frank Z. Stanczyk,Kenneth A. Burry,Suzanne Oparil,Benita S. Katzenellenbogen,Michele L. Nealen,John A. Katzenellenbogen,R. Kent Hermsmeyer +7 more
TL;DR: E3- and 3beta-Adiol-mediated reduction in persistent Ca2+ signals is associated with ER-beta-mediated attenuation of TPR expression and may partly explain estrogen benefits in coronary vascular muscle.