S
Suzanne Oparil
Researcher at University of Alabama at Birmingham
Publications - 941
Citations - 122414
Suzanne Oparil is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Blood pressure & Angiotensin II. The author has an hindex of 106, co-authored 885 publications receiving 113983 citations. Previous affiliations of Suzanne Oparil include Michigan State University & Oregon Health & Science University.
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Urinary sodium excretion predicts blood pressure response to spironolactone in patients with resistant hypertension independent of aldosterone status.
TL;DR: The findings suggest that mineralocorticoid receptor antagonists may be of preferential benefit in counteracting the BP effects of high dietary sodium.
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Effect of hypoxia on the conversion of angiotensin I to II in the isolated perfused rat lung
TL;DR: It is speculated that hypoxia-induced inhibition of AI conversion in vivo may be secondary to the effects of hypoxIA on hemodynamics, and the effect of contact time on the rate ofAI conversion in the lungs is confirmed.
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New 2017 American Heart Association and American College of Cardiology guideline for hypertension in the adults: major paradigm shifts, but will they help to fight against the hypertension disease burden?
TL;DR: The new 2017 High Blood Pressure Clinical Practice Guidelines produced by the American College of Cardiology (ACC) and the AHA in collaboration with many other societies were presented provide major conceptual changes when compared to all previously published guidelines.
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Targeted delivery of human iPS-ECs overexpressing IL-8 receptors inhibits neointimal and inflammatory responses to vascular injury in the rat
Samantha Giordano,Xiangmin Zhao,Dongqi Xing,Fadi G. Hage,Suzanne Oparil,John P. Cooke,Jieun Lee,Karina H. Nakayama,Ngan F. Huang,Yiu-Fai Chen +9 more
TL;DR: It is hypothesized that HiPS-IL8RA/B-ECs transfused intravenously into rats with balloon injury of the carotid artery will target to the injured site and compete with neutrophils, thus inhibiting inflammation and neointima formation and provide a novel strategy to treat vascular injury.
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Hypoxia-induced inhibition of converting enzyme activity: role in vascular regulation.
TL;DR: The altered systemic and pulmonary pressor responsiveness to ANG I and ANG II in hypoxic rats is probably related to mechanisms specific to the renin-angiotensin system, such as inhibition of intrapulmonary angiotENSin-converting enzyme activity and down regulation of ANG II receptors in the systemic circulation.