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Sverre E. Kjeldsen

Researcher at University of Oslo

Publications -  771
Citations -  95426

Sverre E. Kjeldsen is an academic researcher from University of Oslo. The author has contributed to research in topics: Blood pressure & Left ventricular hypertrophy. The author has an hindex of 94, co-authored 735 publications receiving 89059 citations. Previous affiliations of Sverre E. Kjeldsen include University of Michigan & Cornell University.

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Sodium depletion increases platelet and plasma catecholamines in hypertensive men.

TL;DR: Previously untreated 50-year-old men with mild to moderate essential hypertension were given a low sodium diet for 2 weeks and blood platelets may be an integrated measure of plasma catecholamine concentrations during variations caused by sodium depletion.
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Disregard the reported data from the HYGIA project: blood pressure medication not to be routinely dosed at bedtime.

TL;DR: The study ‘Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial’ should have produced over 150 000 long-term blood pressure measurements with a failure rate of less than 10%; which it cannot achieve in clinical use, not even with Spacelabs devices.
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Nifedipine plus candesartan combination increases blood pressure control regardless of race and improves the side effect profile: DISTINCT randomized trial results

TL;DR: N/C combination was effective in participants with hypertension and showed an improved side effect profile compared with N monotherapy, and combination therapy was similarly effective in different racial groups.
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Impact of alcohol habits and smoking on the risk of new-onset atrial fibrillation in hypertensive patients with ECG left ventricular hypertrophy: the LIFE study.

TL;DR: The data suggest that alcohol intake above this level may be marginally deleterious, while no effect of smoking on risk of AF was detected in hypertensive patients with LVH and there were no significant interactions between high alcohol intake and either smoking or gender on the risk of getting AF.